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To preliminarily evaluate the effects of three online intervention models— “Health Education,”“Subsidy,” and “Relay Vaccination”—on HPV vaccination rates among female adolescents aged 15 to 18 in China, as well as the willingness of guardians to delay vaccination and their confidence in vaccines.
Eight secondary schools in Chengdu and Nanjing were recruited using convenience sampling and divided into three groups: “Health Education” (health education video + postcards), “Subsidy” (financial assistance), and “Relay Vaccination” (health education video + postcards +financial assistance). The study subjects were high school girls aged 15 to 18 who had not yet received the HPV vaccine and one guardian per participant. The primary outcome was the rate of first HPV vaccination among high school girls within one-month post-intervention; secondary outcomes included changes in guardians’ willingness to delay vaccination and their confidence in vaccines before and after the intervention.
A total of 238 pairs of participants were included. Within one-month post-intervention, the vaccination rates were 43.9% for the “Relay Vaccination” group, 43.1% for the “Subsidy” group, and 16.7%for the“Health Education” group. The willingness to delay vaccination significantly decreased in the “Relay Vaccination”group (57.89% vs. 46.49%, P=0.004) and the “Health Education” group (50.00% vs. 33.33%, P=0.001), while there was no significant change in the “Subsidy” group (51.72% vs. 48.28%, P=0.688). Prior to the intervention, guardians in all three groups had high confidence in vaccines, and no statistically significant changes were observed post-intervention (P>0.05).
The “Relay Vaccination” and “Subsidy” groups exhibited superior effects on increasing vaccination rates compared to the“Health Education” group. The health education information included in the intervention strategies helped reduce the willingness to delay vaccination. The study conclusions require further validation with a larger sample size.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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