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Study on the association between cardiorespiratory fitness and stroke and its subtypes
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Hui LUO1, Xue TIAN1, Shuo-hua CHEN2, Shou-ling WU2, An-xin WANG3, 4, Yan-xia LUO1
Modern Preventive Medicine | 2025, 52(5) : 831 - 835
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Modern Preventive Medicine | 2025, 52(5): 831-835
• Epidemiology and Statistical Methods •
Study on the association between cardiorespiratory fitness and stroke and its subtypes
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Hui LUO1, Xue TIAN1, Shuo-hua CHEN2, Shou-ling WU2, An-xin WANG3, 4, Yan-xia LUO1
Affiliations
  • School of Public Health, Capital Medical University, Beijing 100069, China
Published: 2025-03-10 doi: 10.20043/j.cnki.MPM.202410150
Outline
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Objective

To investigate the impact of different levels of cardiorespiratory fitness on the occurrence of stroke.

Methods

This study was based on the Kailun cohort study, which included a total of 37 547 participants, followed up until December 31, 2019.Cardiorespiratory fitness (Estimated cardiorespiratory fitness, eCRF) was estimated using a non-exercise algorithm, and the average eCRF values from measurements taken in 2006, 2008, and 2010 were calculated, standardized, and grouped according to gender-specific tertiles. Cox regression models were employed to explore the relationship between varying levels of eCRF and the incidence of stroke and its subtypes.

Results

During a median follow-up of 9.05 (8.67, 9.33) years, a total of 2 100 cases of stroke (5.59%) were observed, including 1 899 (5.06%) ischemic strokes and 226 (0.60%) hemorrhagic strokes. After adjusting for confounding factors, compared to the low average eCRF group, the high eCRF group exhibited a 28% reduction in stroke risk (HR=0.72, 95%CI: 0.62-0.82), a 23% reduction in ischemic stroke risk (HR=0.77, 95%CI: 0.67-0.89), and a 40% reduction in hemorrhagic stroke risk (HR=0.60, 95%CI: 0.39-0.91).

Conclusion

Higher levels of cardiorespiratory fitness can reduce the risk of stroke and its subtypes.

Cardiorespiratory fitness  /  Stroke  /  Ischemic stroke  /  Hemorrhagic stroke
Hui LUO, Xue TIAN, Shuo-hua CHEN, Shou-ling WU, An-xin WANG, Yan-xia LUO. Study on the association between cardiorespiratory fitness and stroke and its subtypes[J]. Modern Preventive Medicine, 2025 , 52 (5) : 831 -835 . DOI: 10.20043/j.cnki.MPM.202410150
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Year 2025 volume 52 Issue 5
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Article Info
doi: 10.20043/j.cnki.MPM.202410150
  • Receive Date：2024-10-12
  • Online Date：2026-03-18
  • Published：2025-03-10
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History
  • Received：2024-10-12
Affiliations
    School of Public Health, Capital Medical University, Beijing 100069, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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