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Risk factors for renal failure in patients with chronic kidney disease complicated by hypertension
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Zhi-min DONG1, Xing-xing ZHUANG2, Zhou-jie SI1, Cai-mei YIN1
Modern Preventive Medicine | 2025, 52(17) : 3247 - 3251
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Modern Preventive Medicine | 2025, 52(17): 3247-3251
• Clinical Medicine and Prevention •
Risk factors for renal failure in patients with chronic kidney disease complicated by hypertension
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Zhi-min DONG1, Xing-xing ZHUANG2, Zhou-jie SI1, Cai-mei YIN1
Affiliations
  • Department of Outpatient, Chaohu Hospital Affiliated to Anhui Medical University, Hefei, Anhui 238000, China
Published: 2025-09-10 doi: 10.20043/j.cnki.MPM.202505380
Outline
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Objective

To analyze the risk factors for renal failure in patients with chronic kidney disease (CKD) complicated by hypertension.

Methods

A total of 230 CKD patients with hypertension admitted to Chaohu Hospital Affiliated to Anhui Medical University from April 2023 to April 2024 were enrolled. According to the occurrence of renal failure, the patients were divided into the renal failure group (n=47) and the non-renal failure group (n=183). Baseline characteristics were compared between the two groups. Lasso regression and multivariate logistic regression were used to screen for risk factors of renal failure.

Results

Among the 230 patients, 47 (20.43%) developed renal failure. Logistic regression analysis revealed that hyperuricemia (OR=3.104, 95% CI: 1.661-5.800), anemia (OR=3.413, 95% CI: 1.706-6.828), hyponatremia (OR=2.852, 95% CI: 1.383-5.882),proteinuria (OR=2.858, 95% CI: 1.318-6.198), advanced age (OR=2.579, 95% CI: 1.396-4.765), and uncontrolled blood pressure (OR=2.211, 95% CI: 1.193-4.096) were independent risk factors for renal failure in CKD patients with hypertension.

Conclusion

CKD patients with hypertension have a high risk of renal failure. Advanced age, uncontrolled blood pressure, hyperuricemia, anemia, hyponatremia, and proteinuria are significant risk factors for renal failure in this population.

Chronic kidney disease complicated by hypertension  /  Renal failure  /  Risk factors
Zhi-min DONG, Xing-xing ZHUANG, Zhou-jie SI, Cai-mei YIN. Risk factors for renal failure in patients with chronic kidney disease complicated by hypertension[J]. Modern Preventive Medicine, 2025 , 52 (17) : 3247 -3251 . DOI: 10.20043/j.cnki.MPM.202505380
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Year 2025 volume 52 Issue 17
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Article Info
doi: 10.20043/j.cnki.MPM.202505380
  • Receive Date：2025-05-25
  • Online Date：2026-03-18
  • Published：2025-09-10
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History
  • Received：2025-05-25
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    Department of Outpatient, Chaohu Hospital Affiliated to Anhui Medical University, Hefei, Anhui 238000, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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