To fit and predict the incidence trend of pulmonary tuberculosis in Guiyang City, assess whether the End TB Strategy target for 2035 (incidence <10 per 100 000 population) can be achieved, and provide a reference for relevant departments to optimize prevention and control measures.
Based on the anonymized tuberculosis case data from Guiyang City between 2010 and 2024, after excluding records with missing onset times and duplicate entries, a transmission dynamics model was constructed by integrating demographic and epidemiological data. Taking into account the latent period of tuberculosis, infection progression, and case detection, the Bayesian method was employed to estimate transmission parameters and predict incidence trends from 2025 to 2050. The effectiveness of various control measures was evaluated through parameter optimization strategies.
The model achieved a mean absolute percentage error (MAPE) of 5.02%, and an R2 of 0.86 in fitting the 2010—2019 data. Projections indicated that under current strategies, Guiyang City would fail to meet the 2035 TB control target. However, with optimized interventions, the target could be achieved two years ahead of schedule.
Enhancing active case detection and preventive treatment for latent TB infections could enable Guiyang City to reach the End TB Strategy’s 2035 goal.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |