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To analyze the vaccination status of hepatitis B vaccine (HepB) among children born to HBsAg positive mothers in Qingdao City, to investigate factors influencing the vaccination timeliness of HepB.
Vaccination data of HepB among children born to HBsAg positive mothers in Qingdao City from 2020 to 2022 was obtained from Shandong immunization information systems. The vaccination rates and timely vaccination rates of HepB were analyzed, and multivariate logistic regression was used to identify factors influencing vaccination timeliness.
A total of 6 232 children born to HBsAg positive mothers were included. The vaccination rate of first dose of HepB (HepB1) was 100%, and the timely vaccination rate (within 12 hours of birth) of HepB1 was 84.88%. The full-course vaccination rate of HepB was 99.73%, and the timely full-course vaccination rate (within six months of birth) was 73.38%. Multivariate logistic regression showed that born in 2021 (OR=1.51, 95%CI: 1.26-1.80), born in 2022 (OR=4.92, 95%CI: 3.91-6.20), born in county-level hospitals (OR=1.65, 95%CI: 1.38-1.96) and private hospitals (OR=2.57, 95%CI: 1.88-3.50), birth weight ≥2.5kg (OR=2.89, 95%CI: 1.88-4.44), gestational age at birth ≥37 weeks (OR=1.83, 95%CI: 1.28-2.61), birth time not between 3 PM and 9 PM (OR=12.63, 95%CI: 10.69-14.95) were promoting factors for the vaccination timeliness of HepB1; Female (OR=1.13, 95%CI: 1.01-1.26) was a promoting factor for the vaccination timeliness of full-course HepB; Gestational age at birth ≥37 weeks (OR=0.73, 95%CI: 0.57-0.95), second birth (OR=0.77, 95%CI: 0.68-0.86), third birth and above (OR=0.57, 95%CI: 0.46-0.70) were risk factors for the vaccination timeliness of full-course HepB.
The vaccination rates of HepB1 and full-course HepB among children born to HBsAg positive mothers in Qingdao City were maintained at a high level, but the timely vaccination rates were relatively low. We should take targeted measures to improve the vaccination timeliness of HepB.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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