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To investigate the dose-response relationship between neck circumference and hypertension using restricted cubic spline modeling.
The data for this study were sourced from the 2023 Zigong Respiratory Health Screening Program. A stratified random sample of Zigong residents aged 35 to 75 years was selected to participate in questionnaire surveys, physical measurements, and health examinations. Logistic regression and restricted cubic spline models were employed to investigate the relationship between neck circumference and hypertension.
A total of 4 142 participants aged 35-75 years were enrolled, with a hypertension prevalenceof 36.5%. After adjusting for confounders, the odds ratios (OR) associated with hypertension prevalencewas 1.20(95%CI: 1.01-1.43) for the low neck circumference group and 1.42(95%CI: 1.17-1.72) for the high neck circumference group. Restricted cubic spline analysis showed a U-shaped nonlinear dose-response relationship between neck circumference and prevalence of hypertension in the overall population and in the noncentrally obese population(P<0.001 for overall trend and P<0.05 for nonlinearity). In contrast, in the centrally obese population, a linear dose-response relationship was demonstrated between prevalence of hypertension and neck circumference(overall trend P<0.001, nonlinear P>0.05).
Neck circumference is strongly associated with hypertension and there is a U-shaped dose-response relationship.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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