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To investigate the status and influencing factors of social frailty in elderly patients on Maintenance Hemodialysis (MHD) and to construct a nomogram prediction model.
A survey was conducted among 340 elderly MHD patients using a general information questionnaire, social frailty scale, hemodialysis self-management scale, Toronto Alexithymia Scale, Family Care Index, and Social Support Rating Scale. Independent influencing factors were identified, and a nomogram prediction model was constructed and evaluated.
The prevalence of social frailty among elderly MHD patients was 28.82%. Binary logistic regression analysis revealed that a history of falls in the past year (OR=3.117, 95% CI: 1.249-7.778), self-care ability (OR=4.058, 95% CI: 2.002-8.228), alexithymia (OR=1.073, 95% CI: 1.009-1.141), family care level (OR=0.744, 95%CI: 0.612-0.903), and social support (OR=0.886, 95% CI: 0.801-0.981) were significant influencing factors for social frailty in elderly MHD patients (all P<0.05). The area under the receiver operating characteristic curve for the constructed model was 0.921(95% CI: 0.893-0.950), with the maximum Youden index being 0.688, an optimal cutoff value of 0.330, sensitivity of 83.7%, and specificity of 85.1%, indicating high discrimination of the model. The Hosmer-Leeshawn test yielded χ2=10.465, P=0.234,suggesting good model fit. Internal validation calibration curves indicated satisfactory calibration of the model. Decision curve analysis demonstrated high clinical utility of the model.
The nomogram prediction model developed in this study is a practical and convenient tool that aids in predicting the risk of social frailty in elderly MHD patients.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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