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To explore whether the newly proposed cardiovascular health indicator LE8 provides greater predictive value for adverse cardiovascular events (ACE) than LS7 in the Chinese population.
Based on the China Health and Nutrition Survey (CHNS), 5 772 participants who had not experienced ACE prior to the 2009 survey were included. The cardiovascular health indicators LE8 and LS7 were calculated, and the Kaplan-Meier method and Cox proportional hazards model were used to estimate the 5-year risk of ACE occurrence. The differences in predictive value for ACE occurrence between the two indicators were compared using C statistics.
For LE8, the participants in the highest percentile had a 5-year ACE risk of 2.3%,whereas those in the lowest percentile had a risk approximately six times higher. The results of the Cox proportional hazards model indicated that the C statistic for LS7 was 0.728 (95%CI: 0.706-0.75), while that for LE8 was 0.726 (95%CI: 0.703-0.748), with no statistically significant difference (P=0.51).
In the Chinese population, both LE8 and LS7 are associated with new ACE. However, LE8 incurs higher collection costs and has not demonstrated superior predictive value; therefore, LS7, which is easier to implement in clinical practice, is recommended as the risk prediction indicator for new cardiovascular events.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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