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Study on the relationship between different trajectories of depression symptoms and stroke risk in community-dwelling elderly
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Jie ZHANG1, Jia-nan LI1, Yu-jie HUANG2, De-min XU2, 3
Modern Preventive Medicine | 2025, 52(7) : 1296 - 1299
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Modern Preventive Medicine | 2025, 52(7): 1296-1299
• Health and Social Behavior •
Study on the relationship between different trajectories of depression symptoms and stroke risk in community-dwelling elderly
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Jie ZHANG1, Jia-nan LI1, Yu-jie HUANG2, De-min XU2, 3
Affiliations
  • School of Public Health, Xiamen University, Xiamen, Fujian 361000, China
Published: 2025-04-10 doi: 10.20043/j.cnki.MPM.202409545
Outline
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Objective

To assess the association between the trajectories of depression symptoms and the risk of stroke in the elderly.

Methods

Data from four waves of the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2018 were utilized.Group-based trajectory modeling was employed to identify the trajectories of depression symptoms, and logistic regression models were used to evaluate the relationship between these trajectories and stroke.

Results

Four trajectories of depression symptoms were identified:low stable (n=2 392, 60.7%), moderate decreasing (n=762, 20.2%), moderate increasing (n=416, 12.3%), and high stable (n=250, 6.8%).During the period from 2015 to 2018, a total of 305 respondents experienced a stroke. Compared to participants with the low stable depression symptom trajectory, those following the moderate decreasing (OR=1.48, 95%CI: 1.09-2.02), moderate increasing (OR=2.22,95%CI: 1.58-3.11), and high stable depression symptom trajectories (OR=1.78, 95%CI: 1.12-2.83) had a higher risk of stroke.

Conclusion

Over time, elderly individuals following moderate decreasing, moderate increasing, and high stable trajectories of depression symptoms exhibited an increased risk of stroke. Long-term depression symptoms may serve as a strong predictor for stroke.

Depression symptoms  /  Community-dwelling elderly  /  Stroke  /  Trajectory  /  CHARLS
Jie ZHANG, Jia-nan LI, Yu-jie HUANG, De-min XU. Study on the relationship between different trajectories of depression symptoms and stroke risk in community-dwelling elderly[J]. Modern Preventive Medicine, 2025 , 52 (7) : 1296 -1299 . DOI: 10.20043/j.cnki.MPM.202409545
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Year 2025 volume 52 Issue 7
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Article Info
doi: 10.20043/j.cnki.MPM.202409545
  • Receive Date：2024-09-29
  • Online Date：2026-03-18
  • Published：2025-04-10
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  • Received：2024-09-29
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    School of Public Health, Xiamen University, Xiamen, Fujian 361000, China
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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