To describe the changes in the burden of depression among Chinese residents from 1990 to 2021 and to forecast future trends, providing reference for the prevention and control of depression.
Based on the 2021 Global Burden of Disease data, indicators such as the number of cases, incidence rate, prevalence rate, and disability-adjusted life years (DALYs) along with DALYs rates were selected to calculate the rate of change. The Join point regression model was employed to calculate the annual percentage change (APC) and average annual percentage change (AAPC) to analyze the trend of disease burden. Future trends were predicted using R software combined with the GM (1,1) model.
In 2021, the total number of depression cases in China was approximately 42.36 million, with an incidence rate of 2 977.354 per 100 000 and a standardized incidence rate of 2 345.079 per 100 000. The total DALYs attributed to depression were 7.8659 million years, with a total DALYs rate of 552.87 per 100 000 and a standardized DALYs rate of 430.61 per 100 000. Compared to 1990, the standardized prevalence rates for the total population, males, and females decreased by 6.39%, 2.4%, and 9.17%, respectively; the standardized incidence rates decreased by 10.79%, 3.96%, and 14.93%; and the standardized DALYs rates decreased by 9.02%, 3.85%, and 12.43%. Join point regression analysis indicated that from 1990 to 1995 and from 2010 to 2015, the standardized incidence rate of depression among the total population in China showed an increasing trend (APC of 1.56% and 1.37%, respectively), while from 1995 to 2000 and 2005 to 2010, it exhibited a decreasing trend (APC of -2.74% and -1.45%,respectively). The standardized prevalence rates from 1990 to 1992, 1992 to 1995, and 2019 to 2021 all showed an upward trend (APC of 1.67%, 0.48%, and 0.96%, respectively), whereas from 1995 to 2000, 2000 to 2005, 2005 to 2010, and 2010 to 2019, they demonstrated a downward trend (APC of -1.06%, -0.22%, -1.02%, and -0.15%, respectively). The standardized DALYs rate increased from 1990 to 1994 (APC of 1.75%) and showed a decreasing trend from 1994 to 2000 and from 2000 to 2006 (APC of-1.55% and -0.46%, respectively).
The burden of depression among Chinese residents is increasing, with a higher burden observed in females. The risk of depression among the elderly should not be overlooked. Continued efforts are needed to enhance public awareness of depression-related health knowledge and implement preventive interventions.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |