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Association between cardiometabolic index and risk of kidney stones in a health screening population
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Sheng-qi ZHENG1, Jia-long WANG1, Ze-xun DENG1, Xin-yu SHEN1, Ye YAO2, Yi-fan LI1
Modern Preventive Medicine | 2025, 52(2) : 198 - 202
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Modern Preventive Medicine | 2025, 52(2): 198-202
Epidemiology and Statistical Methods Advances
Association between cardiometabolic index and risk of kidney stones in a health screening population
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Sheng-qi ZHENG1, Jia-long WANG1, Ze-xun DENG1, Xin-yu SHEN1, Ye YAO2, Yi-fan LI1
Affiliations
  • Department of Urology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, China
Published: 2025-01-25 doi: 10.20043/j.cnki.MPM.202410246
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Objective

To assess the association between the cardiometabolic index (CMI) and the risk of kidney stone prevalence, and to analyze its role across different population subgroups.

Methods

This cross-sectional study included health examination data from 76 624 adults. The association between CMI and the risk of kidney stones was evaluated using multivariable logistic regression models. Stratified analyses were conducted to explore the effect of different population characteristics. A piecewise linear regression model was used to assess the nonlinear relationship between CMI and kidney stone risk.

Results

CMI levels were positively associated with the prevalence of kidney stones, with the prevalence increasing from 4.33% in the lowest tertile to 9.94% in the highest tertile (P<0.001). Even after adjusting for potential confounders, CMI remained significantly associated with an increased risk of kidney stones (OR = 1.15, 95% CI = 1.10-1.20, P<0.001). Stratified analyses showed that the effect of CMI on kidney stone risk was more pronounced in individuals aged ≥60 years (OR = 1.19, 95% CI = 1.08-1.32, P<0.001) and in males (OR = 1.16, 95% CI = 1.10-1.21, P<0.001), while no significant association was found in females (OR = 1.11, 95% CI = 0.96-1.28, P = 0.157). A nonlinear relationship was observed between CMI and kidney stone risk. Risk significantly increased when CMI was <0.73 (OR = 1.15, 95% CI = 1.10-1.20, P<0.001), while the risk plateaued for CMI ≥0.73 (OR = 1.09, 95% CI = 1.03-1.15, P = 0.002).

Conclusion

Elevated CMI is significantly associated with a higher risk of kidney stones, demonstrating a nonlinear threshold effect. As a comprehensive marker reflecting metabolic burden, CMI may be useful for screening and targeting interventions in high-risk populations for kidney stones.

Kidney stone  /  Cardiometabolic index  /  Abdominal obesity  /  Insulin resistance
Sheng-qi ZHENG, Jia-long WANG, Ze-xun DENG, Xin-yu SHEN, Ye YAO, Yi-fan LI. Association between cardiometabolic index and risk of kidney stones in a health screening population[J]. Modern Preventive Medicine, 2025 , 52 (2) : 198 -202 . DOI: 10.20043/j.cnki.MPM.202410246
Year 2025 volume 52 Issue 2
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Article Info
doi: 10.20043/j.cnki.MPM.202410246
  • Receive Date:2024-10-17
  • Online Date:2026-03-18
  • Published:2025-01-25
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  • Received:2024-10-17
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    Department of Urology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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