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To analyze the survival time of HIV/AIDS patients in Hebei province, and to explore the influencing factors, so as to provide basis for improving the quality of life of patients.
Retrospective cohort study was used to collect information of HIV/AIDS in Hebei province from 1989 to 2022. Life table was used to describe the survival status. Log-rank test and Cox regression were used to analysis the influencing factors of survival time.
There were 22 563 cases of HIV/AIDS, with males accounting for 88.7% and homosexual transmission accounting for 62.1%. The average age at the time of discovery was 38.1±13.9. The 1-year,3-year,5-year and 10-year cumulative survival rates of HIV/AIDS patients were 91.46%,88.03%, 85.56% and 79.34%. The risk of death in female was lower than that in male (HR=0.824, 95% CI: 0.713-0.953). The risk of death in patients receiving antiviral treatment was lower than in those who have not received treatment (HR=0.079, 95% CI:0.069-0.091). Baseline CD4 cell counts ranging from 200 to 349 cells/μl (HR=0.451, 95% CI: 0.222-0.914), 350 to 499 cells/μl (HR=0.354, 95% CI: 0.175-0.719), and above 500 cells/μl (HR=0.342, 95% CI: 0.168-0.693) have a lower risk of death. People over 50 years old have a higher risk of death (HR=2.585, 95% CI: 2.143-3.117). Among the sources of case samples, the case death risk of those from HIV testing and counseling was lower than the cases from medical institutions(HR=0.444,95% CI: 0.387-0.510). And the case death risk of those from detainees was lower than the cases from medical institutions(HR=0.417,95% CI: 0.297-0.584).
Gender, educational level, baseline CD4 cell count, sample source, age at discovery, and antiviral treatment were influencing factors on survival time. Early detection, early treatment, strengthening the publicity and education of key groups, paying attention to the elderly cases over 50 years old, and strengthening medical personnel to actively carry out AIDS testing and consulting services have a positive effect on prolonging the survival time of HIV/AIDS cases.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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