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Short term effects of personalized nutritional support on serum albumin in middle-aged and elderly patients
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Xiao-li SHEN1, 2, Jie-ru PENG1, 3, Chun-xia YANG1, Hong-yu LI2, Yu CHENG4, Yue-shan WANG1, Wen-cheng LONG1
Modern Preventive Medicine | 2025, 52(6) : 1058 - 1062
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Modern Preventive Medicine | 2025, 52(6): 1058-1062
Nutrition and Food Hygiene
Short term effects of personalized nutritional support on serum albumin in middle-aged and elderly patients
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Xiao-li SHEN1, 2, Jie-ru PENG1, 3, Chun-xia YANG1, Hong-yu LI2, Yu CHENG4, Yue-shan WANG1, Wen-cheng LONG1
Affiliations
  • Department of Epidemiology and Health Statistics, West China School of Public Health / West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China
Published: 2025-03-25 doi: 10.20043/j.cnki.MPM.202411476
Outline
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Objective

To explore the short-term effects of personalized nutritional support on serum albumin (ALB) levels in middle-aged and elderly patients using real-world data and multiple factors.

Methods

A retrospective study was conducted on patients aged 50 and above who were at nutritional risk in the nutrition consultation cases at the Second People’s Hospital of Chengdu from August 2020 to June 2024. Clinical data and laboratory test results were collected, and patients were grouped according to different nutritional intervention methods. The ALB decline of patients after 1week of nutritional intervention was analyzed, and the impact of different nutritional intervention methods on ALB decline was evaluated using a logistics regression model.

Results

A total of 1 136 patients were included in the study, with 627 patients showing a decrease in ALB and 509 patients showing no decrease in ALB. Univariate analysis revealed statistically significant differences in age, tube feeding, nutritional intervention methods, chronic kidney disease, cerebral infarction, other site infections, and tumor morbidity. Multivariate analysis was conducted with the dietary guidance group as the control group. Oral nutritional supplementation (OR=0.683, 95%CI: 0.500-0.933), personalized nutritional support intervention (OR=0.409, 95% CI: 0.279-0.601), and other site infections (OR=0.776, 95% CI: 0.607-0.994) were protective factors for ALB decline; Tube feeding (OR=1.766, 95% CI: 1.317-2.369) and cerebral infarction (OR=1.866,95% CI: 1.424-2.444) are risk factors for the decline of ALB.

Conclusion

Personalized nutritional support can effectively prevent the decline of serum albumin in middle-aged and elderly hospitalized patients, and has potential clinical value.

Malnutrition  /  Personalized nutritional support  /  Real world research  /  Serum albumin
Xiao-li SHEN, Jie-ru PENG, Chun-xia YANG, Hong-yu LI, Yu CHENG, Yue-shan WANG, Wen-cheng LONG. Short term effects of personalized nutritional support on serum albumin in middle-aged and elderly patients[J]. Modern Preventive Medicine, 2025 , 52 (6) : 1058 -1062 . DOI: 10.20043/j.cnki.MPM.202411476
Year 2025 volume 52 Issue 6
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Article Info
doi: 10.20043/j.cnki.MPM.202411476
  • Receive Date:2024-11-25
  • Online Date:2026-03-18
  • Published:2025-03-25
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  • Received:2024-11-25
Affiliations
    Department of Epidemiology and Health Statistics, West China School of Public Health / West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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