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Research progress on the epidemiology and pathogenesis of severe fever with thrombocytopenia syndrome virus
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Dan LI1, 2, 3, Xue-jie YU2, Chuan-min ZHOU4
Modern Preventive Medicine | 2025, 52(6) : 961 - 966
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Modern Preventive Medicine | 2025, 52(6): 961-966
• Special Column On Major Disease Prevention and Control •
Research progress on the epidemiology and pathogenesis of severe fever with thrombocytopenia syndrome virus
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Dan LI1, 2, 3, Xue-jie YU2, Chuan-min ZHOU4
Affiliations
  • Hubei Provincial Center for Disease Control and Prevention, Institute for Infectious Disease Prevention and Control, Wuhan， Hubei 430079, China
Published: 2025-03-25 doi: 10.20043/j.cnki.MPM.202411494
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Severe fever with thrombocytopenia syndrome virus (SFTSV) is a highly pathogenic tick-borne bunyavirus that can cause severe viral hemorrhagic fever (SFTS), with a case fatality rate of up to 30%. SFTSV was first identified in 2010, which is primarily transmitted through tick bites but can also be transmitted to humans by sick people or infected cats and dogs. The main clinical manifestations of SFTS include high fever, gastrointestinal symptoms, thrombocytopenia, and leukopenia, with severe cases potentially resulting in death due to multi-organ failure. In 2017, the World Health Organization (WHO) listed SFTS as a priority disease with the potential to cause a public health emergency of international concern. SFTS cases have been reported in China, East Asia, and Southeast Asia, making it an important public health issue. In China, SFTS cases have been reported in 27 provincesincluding Henan, Hubei, Shandong, Anhui, Liaoning, Zhejiang, and Jiangsu. Additionally, SFTS cases have been identified in East and Southeast Asian countries such as South Korea, Japan, Vietnam, Myanmar, Thailand, and Pakistan. This review summarizes the epidemiology and pathogenesis of SFTSV, providing a basis for better understanding the mechanisms of immune evasion and developing effective countermeasures.

Severe fever with thrombocytopenia syndrome virus  /  Epidemiology  /  Immune evasion  /  Pathogenic mechanism
Dan LI, Xue-jie YU, Chuan-min ZHOU. Research progress on the epidemiology and pathogenesis of severe fever with thrombocytopenia syndrome virus[J]. Modern Preventive Medicine, 2025 , 52 (6) : 961 -966 . DOI: 10.20043/j.cnki.MPM.202411494
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doi: 10.20043/j.cnki.MPM.202411494
  • Receive Date：2024-11-26
  • Online Date：2026-03-18
  • Published：2025-03-25
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  • Received：2024-11-26
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    Hubei Provincial Center for Disease Control and Prevention, Institute for Infectious Disease Prevention and Control, Wuhan， Hubei 430079, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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