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Impact of hypertension diagnosis on depressive symptoms in Chinese middle-aged and elderly individuals
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Xiao-xiao LIU, Kai-xi YANG, Sai-long SHI, Yang WAN
Modern Preventive Medicine | 2025, 52(6) : 1131 - 1137
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Modern Preventive Medicine | 2025, 52(6): 1131-1137
Clinical Medicine and Prevention
Impact of hypertension diagnosis on depressive symptoms in Chinese middle-aged and elderly individuals
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Xiao-xiao LIU, Kai-xi YANG, Sai-long SHI, Yang WAN
Affiliations
  • West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China
Published: 2025-03-25 doi: 10.20043/j.cnki.MPM.202411284
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Objective

To explore the impact of hypertension diagnosis and measured blood pressure on depressive symptoms in middle-aged and older adults, providing evidences for depression prevention in this population.

Methods

Data from four waves (2013-2020) of the China Health and Retirement Longitudinal Study (CHARLS) were analyzed, including a total of 4 106 participants aged 45 and older. A linear mixed-effects model was used to examine the effect of hypertension on depressive symptoms.

Results

In the univariate analysis, compared to respondents who with undiagnosed hypertension (32.64%), those diagnosed with hypertension showed a higher proportion of depressive symptoms (33.51%). After adjusting for covariates in the multivariate analysis, diagnosed hypertension (OR=1.05, P=0.003) remained associated with a higher risk of depression. However, elevated blood pressure without diagnosis did not have a significant effect on depressive symptoms (OR=0.99, P=0.454).

Conclusion

Hypertension diagnosis is associated with an increased risk of depressive symptoms among middle-aged and elderly individuals. Therefore, clinicians are advised to monitor not only blood pressure control in hypertensive patients but also their mental health, providing psychological support to prevent emotional issues that may arise from the diagnosis, thus enhancing patients’ quality of life.

Hypertension  /  Depression  /  Elderly
Xiao-xiao LIU, Kai-xi YANG, Sai-long SHI, Yang WAN. Impact of hypertension diagnosis on depressive symptoms in Chinese middle-aged and elderly individuals[J]. Modern Preventive Medicine, 2025 , 52 (6) : 1131 -1137 . DOI: 10.20043/j.cnki.MPM.202411284
Year 2025 volume 52 Issue 6
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Article Info
doi: 10.20043/j.cnki.MPM.202411284
  • Receive Date:2024-11-14
  • Online Date:2026-03-18
  • Published:2025-03-25
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  • Received:2024-11-14
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    West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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