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A prospective cohort study on the relationship between muscle mass and disability among the elderly in China
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Yan-fang HONG1, Yu ZHANG2, Dan-dan XU1, Li-jing WU1, Jun-qiang TAO1
Modern Preventive Medicine | 2025, 52(6) : 1125 - 1130
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Modern Preventive Medicine | 2025, 52(6): 1125-1130
• Disease Control and Prevention •
A prospective cohort study on the relationship between muscle mass and disability among the elderly in China
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Yan-fang HONG1, Yu ZHANG2, Dan-dan XU1, Li-jing WU1, Jun-qiang TAO1
Affiliations
  • Department of Neurosurgery, Second People's Hospital of Yuhuan City, Taizhou, Zhejiang 317600, China
Published: 2025-03-25 doi: 10.20043/j.cnki.MPM.202408444
Outline
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Objective

To explore the relationship between muscle mass and disability in the elderly.

Methods

This study is based on the tracking survey data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) from 2008 to 2018, utilizing Cox regression and constructing restricted cubic spline models to analyze the dose-response relationship between muscle mass and disability in the elderly.

Results

A total of 2 165 elderly patients were followed up 4 times for an average of 10 years. Among them, 603 (27.8%) developed disability. After adjusting for confounders, muscle mass affected disability in the elderly(HR=0.879,95%CI:0.822-0.939). The RCS results showed that the association between muscle mass and disability risk in older adults was non-linear in both older men(Poverall trend<0.05,Pnon-linear<0.05) and older women(Poverall trend<0.05, Pnon-linear<0.05). It is suggested that ASMI level of 7.2 (kg/m2) and above should be maintained in elderly men and 5.2 (kg/m2) and above in elderly women.

Conclusion

Muscle mass is associated with disability in the elderly. Maintenance or improvement of muscle mass can improve the quality of life in the elderly.

Muscle mass  /  Incapacitation  /  The elderly  /  Gender difference  /  Restricted cubic splines
Yan-fang HONG, Yu ZHANG, Dan-dan XU, Li-jing WU, Jun-qiang TAO. A prospective cohort study on the relationship between muscle mass and disability among the elderly in China[J]. Modern Preventive Medicine, 2025 , 52 (6) : 1125 -1130 . DOI: 10.20043/j.cnki.MPM.202408444
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Year 2025 volume 52 Issue 6
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Article Info
doi: 10.20043/j.cnki.MPM.202408444
  • Receive Date：2024-08-29
  • Online Date：2026-03-18
  • Published：2025-03-25
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  • Received：2024-08-29
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    Department of Neurosurgery, Second People's Hospital of Yuhuan City, Taizhou, Zhejiang 317600, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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