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To understand the current status of medication adherence in patients with HIV/AIDS who have failed antiretroviral therapy and to analyze the mediating effect of anxiety in the influence of family care on medication adherence.
A total of 600 patients with HIV/AIDS who failed antiretroviral therapy were included as study subjects, and data on patients’ demographic characteristics, behavioral characteristics, anxiety, family caring and medication adherence were collected through telephone interviews, and mediation analyses were used to analyze the mediating effect of anxiety on the relationship between family caring and medication adherence.
In this survey 29.33% of the population had family care disorder, 15.8% were in anxiety and 56.0% had good medication adherence. The mean score of medication adherence was moderate at 7.15±1.38. Anxiety in HIV/AIDS antiretroviral treatment failure patients fully mediated the effect of family care on medication adherence. The mediating effect (0.033) (95%CI: 0.017-0.053) accounted for 47.8% of the total effect (0.069) (95%CI: 0.033-0.105).
The percentage of local HIV/AIDS patients with good adherence to medication in patients who have failed antiretroviral therapy is relatively low. By increasing the level of family care and helping patients to alleviate anxiety, medication adherence can be effectively improved and treatment outcomes can be improved.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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