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Relationship between the ratio of serum uric acid to high-density lipoprotein cholesterol and abdominal aortic calcification
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Zhen WANG1, Xiao-qian WANG1, Ling-wei ZHANG2, Xiao-tian CHEN1
Modern Preventive Medicine | 2025, 52(10) : 1915 - 1920
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Modern Preventive Medicine | 2025, 52(10): 1915-1920
Clinical Medicine and Prevention
Relationship between the ratio of serum uric acid to high-density lipoprotein cholesterol and abdominal aortic calcification
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Zhen WANG1, Xiao-qian WANG1, Ling-wei ZHANG2, Xiao-tian CHEN1
Affiliations
  • Department of Clinic Nutrition, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu 210000, China
Published: 2025-05-25 doi: 10.20043/j.cnki.MPM.202412476
Outline
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Objective

To investigate the association between UHR and abdominal aortic calcification (AAC) in people aged≥40.

Methods

We used data from the 2013—2014 National Health and Nutrition Examination Survey (NHANES), including a total of 3 008 participants. Multiple logistic regression, subgroup analysis and restricted cubic spline (RCS) analysis were used to explore the correlation between UHR and AAC prevalence.

Results

UHR was positively associated with AAC risk in all participants. Compared with the lowest UHR quartile, the highest quartile had a 134.6% increased risk of AAC (OR=2.346, 95%CI: 1.594-3.453). Interaction analysis showed that there was no significant interaction between UHR grouping and gender or age. Gender stratification showed a 213.6% increase in AAC in the Q4 group of females compared with the Q1 group (OR=3.136, 95%CI: 1.884-5.221), while no statistical significance was achieved in males (P=0.113). Age stratification revealed that for those over 60 years old, the risk of AAC in the Q2, Q3, and Q4 groups increased by 118.6% (OR=2.186, 95%CI: 1.140-4.191), 147.4% (OR=2.474, 95%CI: 1.464-4.181), and 347.8% (OR=4.478, 95%CI: 2.580-7.773) compared with the Q1 group, respectively, while in the 40-60 years old group, it did not reach statistical significance (P=0.338). RCS analysis showed that there was a nonlinear relationship between UHR and AAC.

Conclusion

s UHR is an independent risk factor for AAC, and the higher level of UHR, the higher risk of AAC. The association between UHR and AAC is more significant in females and people over 60 years old.

AAC  /  UHR  /  NHANES  /  Cross-sectional study
Zhen WANG, Xiao-qian WANG, Ling-wei ZHANG, Xiao-tian CHEN. Relationship between the ratio of serum uric acid to high-density lipoprotein cholesterol and abdominal aortic calcification[J]. Modern Preventive Medicine, 2025 , 52 (10) : 1915 -1920 . DOI: 10.20043/j.cnki.MPM.202412476
Year 2025 volume 52 Issue 10
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Article Info
doi: 10.20043/j.cnki.MPM.202412476
  • Receive Date:2024-12-27
  • Online Date:2026-03-18
  • Published:2025-05-25
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  • Received:2024-12-27
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    Department of Clinic Nutrition, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu 210000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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