PDF
Full
Outline
To investigate the predictive value of infection-related blood indexes combined with palliative performance scale (PPS) score in 14-day survival of patients with pulmonary infection after palliative treatment.
A total of 111 inpatients with pulmonary infection treated in the Department of Palliative Medicine, West China Fourth Hospital of Sichuan University from January 2022 to December 2022 were divided into survival group (n = 53) and death group (n = 58) according to the survival condition of 14 days after treatment. Age, sex, prevalence, infection-related blood index level, and PPS score of the two groups were compared by univariate analysis. Multivariate COX regression analysis was used to analyze the factors affecting the 14-day survival prognosis of patients with pulmonary infection after palliative treatment. The nomogram was constructed and the receiver operating characteristic (ROC) curve was used to verify the predictive performance of the model. The reliability of the model was determined by calibration curve and the clinical practicability of the model was evaluated by decision curve analysis (DCA).
Compared with the 14-day survival group, the palliative treatment group had lower PPS score, higher C-reactive protein, procalcitonin, white blood cell, and neutrophil count, and the difference was statistically significant (P<0.05). The results of multivariate COX regression analysis showed that high procalcitonin level (HR=2.201, 95%CI:1.394-3.143) and low PPS score were independent risk factors for poor prognosis of patients with pulmonary infection after palliative treatment for 14 days (with reference to < 20%, 20%-30%: HR=0.333, 95%CI: 0.183-0.606; 40%-50%: HR=0.125,95%CI: 0.043-0.362; > 50%: HR=0.107, 95%CI: 0.014-0.814). The nomogram was constructed based on procalcitonin combined with PPS score. The area under the ROC curve (AUC value: 0.864, 95%CI: 0.809-0.919), calibration curve, and DCA curve results showed that the model had good predictive efficiency and clinical practicability compared with single index prediction.
Procalcitonin level combined with PPS score is a good predictor of poor prognosis in patients with pulmonary infection after palliative treatment for 14 days.
PDF
48
21
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
