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Analysis of treatment outcome and survival of patients with multi-drug resistant tuberculosis in Henan Province from 2011 to 2021
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Shuo WANG, Wei-dong WANG, Meng-ya HE, Yan-qiu ZHANG, Ding-yong SUN
Modern Preventive Medicine | 2024, 51(9) : 1713 - 1718
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Modern Preventive Medicine | 2024, 51(9): 1713-1718
• Clinical Medicine and Prevention •
Analysis of treatment outcome and survival of patients with multi-drug resistant tuberculosis in Henan Province from 2011 to 2021
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Shuo WANG, Wei-dong WANG, Meng-ya HE, Yan-qiu ZHANG, Ding-yong SUN
Affiliations
  • Henan Center for Disease Control and Prevention, Zhengzhou, Henan 450016, China
Published: 2024-05-10 doi: 10.20043/j.cnki.MPM.202311402
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Objective

To investigate the related factors of death in patients with drug-resistant tuberculosis in Henan Province.

Methods

The data of tuberculosis patients diagnosed in all 18 prefecture-level cities and 2 directly administered counties in Henan Province from 2011 to 2021 were selected. The patients with complete course of treatment and treatment outcome were selected. The cumulative survival rate was calculated by Kaplan-Meier method, and Cox proportional hazard regression was used to identify the factors affecting the survival time of patients.

Results

Among the 1 078 patients with drug-resistant tuberculosis, a total of 66 patients (6.1%) died, and the cumulative survival rate within 30 months was 90.1%. In total 50% of the patients died within 10 months. After controlling other factors, age (HR=1.053, 95%CI: 1.029-1.087), XDR-TB patients (HR=3.032, 95%CI: 1.584-5.767), smoking (HR=1.879, 95%CI: 1.006-3.509) and BMI (HR=0.294, 95%CI: 0.088-0.978) were the main risk factors for death of tuberculosis patients during treatment.

Conclusion

Among drug-resistant tuberculosis patients in Henan Province, elderly patients, XDR-TB patients, smoking patients and patients with BMI less than 18.5 have a relatively higher risk of death. Additional support should be provided for the treatment of these patients to reduce mortality.

Survival analysis  /  Multi-drug resistant tuberculosis  /  Extensively drug resistant tuberculosis  /  Risk factors
Shuo WANG, Wei-dong WANG, Meng-ya HE, Yan-qiu ZHANG, Ding-yong SUN. Analysis of treatment outcome and survival of patients with multi-drug resistant tuberculosis in Henan Province from 2011 to 2021[J]. Modern Preventive Medicine, 2024 , 51 (9) : 1713 -1718 . DOI: 10.20043/j.cnki.MPM.202311402
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Year 2024 volume 51 Issue 9
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Article Info
doi: 10.20043/j.cnki.MPM.202311402
  • Receive Date：2023-11-21
  • Online Date：2026-03-18
  • Published：2024-05-10
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  • Received：2023-11-21
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    Henan Center for Disease Control and Prevention, Zhengzhou, Henan 450016, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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