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Objective To analyze the epidemiological characteristics and treatment-related deaths within 12 months of HIV/AIDS patients aged 50 and above reported in a province, providing a basis for targeted prevention and control measures. Methods Data on HIV/AIDS cases aged 50 and above reported in a province from 2010 to 2019 were collected from the China CDC Information System for Comprehensive Prevention and Control of AIDS, and the epidemiological characteristics and treatment-related deaths within 12 months were analyzed. The comparison of rates was performed using the χ2 test, trend changes were analyzed using the trend χ2 test, and the comparison of CD4+ T lymphocyte detection results between groups was performed using non-parametric tests. Results From 2010 to 2019, a total of 2 875 cases of HIV/AIDS aged 50 and above were reported in the province, accounting for 19.4% of the total cases (14 819 cases). The proportion of new cases increased from 10.3% in 2010 to 24.6% in 2019, with a statistically significant difference (χ2trend =126.741, P < 0.001), and the annual reported incidence showed an increasing trend (χ2trend=936.208, P < 0.001). The male-to-female ratio was 5.3:1, with an average age of (58.40±7.50) years. The majority were farmers, accounting for 49.0% (1 408/2 875). The primary education level accounted for 42.0%(1 208/2 875). The majority were identified by medical institutions, accounting for 64.5% (1 854/2 875); sexual transmission was the primary route, accounting for 96.8% (2 784/2 875). Among male cases, same-sex transmission accounted for 49.5% (1 423/2 416). Among female cases, non-marital heterosexual transmission and spousal transmission accounted for 49.0% (212/433) and 51.0% (221/433), respectively. The median CD4+ T lymphocyte count at the initial test was 266 cells/mm3. There was a statistically significant difference in CD4+ T lymphocyte counts between males and females (Z=-5.395, P < 0.001). The treatment rate within 12 months of diagnosis was 56.7% (1 632/2 875), showing an increasing trend each year (χ2trend=115.054, P < 0.001). The mortality rate within 12 months of diagnosis was 15.2% (433/2,875), showing a decreasing trend each year (χ2trend=61.654, P < 0.001). Conclusion The number and proportion of HIV/AIDS cases aged 50 and above in the province have been increasing annually. It is necessary to strengthen targeted health education and interventions for this population as well as expand testing to achieve early detection and treatment.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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