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To investigate the relationship between the weight-adjusted waist index (WWI) and chronic kidney disease (CKD) among the middle-aged and elderly population in China.
This study included 5 630 individuals aged 45 and older who participated in the China Health and Retirement Longitudinal Survey (CHARLS) in 2011 and 2015. The Cox proportional hazards regression model was employed to analyze the association between WWI, treated as a continuous variable and categorized into quartiles, and the risk of CKD. Additionally, a restricted cubic spline (RCS) model was used to explore the dose-response relationship between WWI and CKD.
During the four-year follow-up, 187 participants developed CKD,resulting in an incidence rate of 3.32%. After adjusting for all covariates, each unit increase in WWI was associated with a 33%increase in the risk of CKD (HR: 1.33, 95%CI: 1.10-1.62). In the highest quartile of WWI, the risk of CKD was 2.30 times greater compared to the lowest quartile (HR=2.30, 95%CI: 1.37-3.86). The RCS curve indicated a nonlinear dose-response relationship between WWI and CKD (Pfornon-linear < 0.05).
There is a positive correlation between WWI and the risk of CKD among the middle-aged and elderly population in China, exhibiting a significant nonlinear dose-response relationship.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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