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Association between physical activity level and circadian syndrome in Chinese middle-aged and elderly people
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Jun-ying ZHAI1, Ting WANG2, Tian-wei ZHANG1, Li ZHOU1
Modern Preventive Medicine | 2025, 52(8) : 1441 - 1447
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Modern Preventive Medicine | 2025, 52(8): 1441-1447
• Health and Social Behavior •
Association between physical activity level and circadian syndrome in Chinese middle-aged and elderly people
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Jun-ying ZHAI1, Ting WANG2, Tian-wei ZHANG1, Li ZHOU1
Affiliations
  • Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
Published: 2025-04-25 doi: 10.20043/j.cnki.MPM.202411414
Outline
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Objective

To explore the association between physical activity level (PAL) and Circadian syndrome (CircS) in Chinese middle-aged and elderly population.

Methods

Based on the 2013 China Health and Retirement Longitudinal Study (CHARLS) data, middle-aged and elderly people ≥45 years old with complete key data were selected. The association between PAL and CircS was analysed by multiple logistic regression. In addition, subgroup analyses, interaction tests, smoothed curve fitting, and threshold effect analyses were performed.

Results

A total of 5 851 middle-aged and older adults were included as study subjects, with a prevalence of CircS of 24.18% and PAL of 4 548 (1 732.5, 10 584)(MET-min/w). Fully adjusted multivariate logistic regression showed a significant negative association between PAL and CircS prevalence (OR=0.73, 95% CI: 0.62-0.87; P<0.001). The consistency of this association was confirmed by subset analyses and interaction tests for multiple subgroups. Smoothed curve fitting and threshold effect analyses revealed a nonlinear relationship with a threshold of 3 810 MET-min/w.

Conclusion

There is a negative association between the PAL and the risk of developing CircS. Moderate physical activity may allow early intervention in individuals at risk for CircS.

Circadian syndrome  /  Physical activity level  /  Middle-aged and elderly population  /  China Health and Retirement Longitudinal Study
Jun-ying ZHAI, Ting WANG, Tian-wei ZHANG, Li ZHOU. Association between physical activity level and circadian syndrome in Chinese middle-aged and elderly people[J]. Modern Preventive Medicine, 2025 , 52 (8) : 1441 -1447 . DOI: 10.20043/j.cnki.MPM.202411414
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Year 2025 volume 52 Issue 8
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Article Info
doi: 10.20043/j.cnki.MPM.202411414
  • Receive Date：2024-11-21
  • Online Date：2026-03-17
  • Published：2025-04-25
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  • Received：2024-11-21
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Affiliations
    Department of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
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小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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