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Willingness and influencing factors of using pre-exposure prophylaxis among men who have sex with men in China: a meta -analysis
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Xiao-cui ZOU1, 2, Xiao-rong MAO2, 3, Yue LI2, 4, Qin MAO2, 5, Wei ZHENG2, 6, Qing-hua JIANG7
Modern Preventive Medicine | 2024, 51(8) : 1499 - 1506
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Modern Preventive Medicine | 2024, 51(8): 1499-1506
• Disease Control and Prevention •
Willingness and influencing factors of using pre-exposure prophylaxis among men who have sex with men in China: a meta -analysis
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Xiao-cui ZOU1, 2, Xiao-rong MAO2, 3, Yue LI2, 4, Qin MAO2, 5, Wei ZHENG2, 6, Qing-hua JIANG7
Affiliations
  • Department of Hepatobiliary Surgery, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China
Published: 2024-04-25 doi: 10.20043/j.cnki.MPM.202312052
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Objective

To systematically review the willingness to use pre-exposure prophylaxis (PrEP) and related factors among men who have sex with men (MSM) in China.

Methods

CNKI, VIP, Wanfang Data, CBM, EMbase, CINAHL, Pubmed, The Cochrane Library and Web of Science were searched from inception to August 16, 2023.

Results

A total of 31 articles with 31 390 participants were included. The results of meta-analysis showed that the awareness rate of PrEP was 46.70% (95% CI: 34.14-59.47), the willingness rate of PrEP use was 61.49% (95% CI: 51.58-70.95), and the use rate of PrEP was 3.41% (95% CI:0.07-10.62). Age≥40 years (OR=1.90, 95% CI:1.47-2.57), HIV testing history (OR=2.13, 95% CI:1.63-2.80), awareness of PrEP (OR=2.80, 95% CI:1.86-4.24), online sexual partner seeking (OR=1.44, 95% CI:1.04-2.00), no regular sexual partner (OR=1.69, 95% CI:1.32-2.17), oral sex/anal sex behavior (OR=1.86, 95% CI:1.32-2.61), number of homosexual anal sex partners in the past 6 months>5 (OR=1.86，95% CI:1.32-2.61), Having oral or anal sex in the past year (OR=1.40，95% CI:1.19-1.65) was the promoting factor of PrEP use, while uncertain sexual orientation (OR=0.60, 95% CI:0.41-0.89) and always using condom in the past 6 months (OR=0.47, 95% CI:0.29-0.75) were the barriers.

Conclusion

The rate of MSM PrEP awareness and willingness to use is high in China, but the rate of PrEP use is low; more factors influence the willingness to use PrEP.

Men who have sex with men  /  Pre-exposure prophylaxis  /  Willingness  /  Influence factors  /  Meta analysis
Xiao-cui ZOU, Xiao-rong MAO, Yue LI, Qin MAO, Wei ZHENG, Qing-hua JIANG. Willingness and influencing factors of using pre-exposure prophylaxis among men who have sex with men in China: a meta -analysis[J]. Modern Preventive Medicine, 2024 , 51 (8) : 1499 -1506 . DOI: 10.20043/j.cnki.MPM.202312052
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Year 2024 volume 51 Issue 8
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Article Info
doi: 10.20043/j.cnki.MPM.202312052
  • Receive Date：2023-12-04
  • Online Date：2026-03-16
  • Published：2024-04-25
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  • Received：2023-12-04
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    Department of Hepatobiliary Surgery, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China
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