To investigate the survival situation and influencing factors of patients receiving antiretroviral therapy (ART) in Jinjiang district, Chengdu, and to evaluate the effect of ART and optimize follow-up management mode.
The follow-up data of HIV/AIDS patients were collected from the National HHART reporting system during 2012-2022. Life table method was used to describe the survival status, and Cox proportion hazard regression model was used to identify the factors related to survival time.
A total number of 2 113 cases was enrolled, the average age of the study subjects was (38.65±15.65) years old, and the average survival time was 132.41 months. By the time of the follow-up observation was terminated, 71 cases died. The accumulated survival rates of 1, 3, 5 and 10 year after initiating ART were 97.86%, 96.78%, 96.43% and 95.73%, respectively. The multivariable Cox proportional hazards regression analysis indicated that the risk of death. The HR of 40-49 years, 50-59 years, and ≥60 years group were 4.233(95% CI: 1.608-11.139), 3.997(95% CI: 1.265-12.623), 19.994(95% CI: 7.424-53.846) relative to <30 years group, respectively. The HR of unmarried group was 3.359(95% CI: 1.495-7.546) relative to married group. The HR of interval time between diagnosis and treatment 31-60 days, 61-90 days group were 2.337(95% CI: 1.311-4.165), 3.430(95% CI: 1.608-7.319) relative to ≤30 days group. The HR of 200-349 cells/μl and ≥350 cells/μl baseline CD4+T cells counts group were 0.262(95% CI: 0.135-0.509), 0.206(95% CI: 0.080-0.530) relative to <200 cells/μl group. The HR of related symptoms before treatment group was 2.088(95% CI: 1.051-4.148) relative to no related symptoms before treatment group.
The effect of patients receiving ART in Jinjiang District is remarkable. ART coverage should be extended, and corresponding follow-up management measures and intervention means should be developed according to the actual situation in Jinjiang District.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |