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Associations of fasting plasma glucose, 2-hour postload glucose, glycated hemoglobin, and triglyceride-glucose index with cancer risk: a prospective cohort study
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Ju-zhong KE, Kang WU, Xiao-lin LIU, Hua QIU, Xiao-nan WANG, Zhi-tao LI, Yi ZHOU
Modern Preventive Medicine | 2024, 51(6) : 988 - 993
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Modern Preventive Medicine | 2024, 51(6): 988-993
Epidemiology and Statistical Methods Advances
Associations of fasting plasma glucose, 2-hour postload glucose, glycated hemoglobin, and triglyceride-glucose index with cancer risk: a prospective cohort study
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Ju-zhong KE, Kang WU, Xiao-lin LIU, Hua QIU, Xiao-nan WANG, Zhi-tao LI, Yi ZHOU
Affiliations
  • Pudong New Area Centers for Disease Control and Prevention, Shanghai 200136, China
Published: 2024-03-25 doi: 10.20043/j.cnki.MPM.202311489
Outline
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Objective

To explore the association of different glycemic measures and the risk of cancer.

Methods

A prospective cohort study conducted in Pudong New Area was used to solve the question. Cox proportional hazard model and Restricted cubic spline (RCS) regression model were used to explore the associations between different glycemic measures and the risk of cancer.

Results

A total of 411 new cancer patients were observed after median 7.78 years follow-up, accumulative person-year incidence rates were 7.12/1 000. After multi-variable adjustment, the HR (95% CI) of elevated FPG and 2hPG were 1.10 (1.03~1.18) and 1.11 (1.02~1.20), respectively. The association between FPG and cancer risk showed a linear dose-response relationship; the association between 2hPG and cancer risk showed a trend toward a U-shaped dose-response relationship.

Conclusion

FPG and 2hPG are important risk factors for cancer, attention should be paid in the prevention and intervention of cancer.

Fasting plasma glucose  /  2-hour postload glucose  /  Hemoglobin A1c  /  Triglyceride glucose index  /  Cancer
Ju-zhong KE, Kang WU, Xiao-lin LIU, Hua QIU, Xiao-nan WANG, Zhi-tao LI, Yi ZHOU. Associations of fasting plasma glucose, 2-hour postload glucose, glycated hemoglobin, and triglyceride-glucose index with cancer risk: a prospective cohort study[J]. Modern Preventive Medicine, 2024 , 51 (6) : 988 -993 . DOI: 10.20043/j.cnki.MPM.202311489
Year 2024 volume 51 Issue 6
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doi: 10.20043/j.cnki.MPM.202311489
  • Receive Date:2023-11-27
  • Online Date:2026-03-16
  • Published:2024-03-25
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  • Received:2023-11-27
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    Pudong New Area Centers for Disease Control and Prevention, Shanghai 200136, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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