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To analyze the trend of incidence and mortality of liver cancer due to HBV (hepatitis B virus, HBV) infection in China from 1990 to 2019, and to provide a scientific basis for the prevention and control of liver cancer.
Using the Global Burden of Disease database, the incidence and mortality of liver cancer due to HBV infection in China were analysed from 1990 to 2019, and a Joinpoint regression model was applied to analyse the trends in the incidence and mortality of liver cancer due to HBV infection. An age-period-cohort model was constructed to analyze the effects of three factors: age, period, and cohort on changes in morbidity and mortality.
The overall trend of the standardized incidence rate and the standardized mortality rate of liver cancer due to HBV infection for both men and women in China from 1990 to 2019 showed a decreasing trend. The average annual rates of change in the standardized incidence rate for men and women were -2.94% and -4.24%, respectively. And the average annual rates of change in the standardized mortality rate were -3.35% and -4.45%, respectively. The age-period-cohort model showed that the risk of morbidity and mortality for males and females tended to increase and then decrease with age, and the overall trend decreased with period and birth cohort, but there was a slight increase locally.
The incidence and mortality rates of liver cancer caused by HBV infection show a substantial downward trend from 1990 to 2019. In the future, the problem of HBV-induced liver cancer will remain serious, and it is recommended that hepatitis B (Hepatitis B) vaccination be expanded among high-risk groups, and that public education on health behaviors be strengthened and early screening for liver cancer be actively carried out.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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