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The current status and influencing factors of HPV vaccination willingness among college students in China: a systematic review and meta-analysis
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Yue-lin WANG1, Yun-lan JIANG2, Le LI1, Hong CHEN1, Jing WANG1, Meng-jie ZHANG1, Xiao-yu BAI1, Sen-lin WU1
Modern Preventive Medicine | 2025, 52(18) : 3424 - 3431
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Modern Preventive Medicine | 2025, 52(18): 3424-3431
Disease Control and Prevention
The current status and influencing factors of HPV vaccination willingness among college students in China: a systematic review and meta-analysis
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Yue-lin WANG1, Yun-lan JIANG2, Le LI1, Hong CHEN1, Jing WANG1, Meng-jie ZHANG1, Xiao-yu BAI1, Sen-lin WU1
Affiliations
  • College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China
Published: 2025-09-25 doi: 10.20043/j.cnki.MPM.202504095
Outline
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Objective

To systematically evaluate the willingness to receive HPV vaccination and influencing factors among college students in China.

Methods

Relevant studies were retrieved from PubMed, Embase, Web of Science, The Cochrane Library, CINAHL, PsycINFO, China Biomedical Literature Database, CNKI, Wanfang Database, and VIP Database from the establishment of the databases to March 12, 2025. Meta-analysis was conducted using Stata 17.0 and RevMan 5.4 to assess the willingness to receive HPV vaccination and influencing factors among college students.

Results

A total of 35 studies involving 62 958 samples were included. The meta-analysis results showed that the willingness rate of college students in China to receive HPV vaccination was 67.0%. Female (OR=3.47, 95% CI: 2.49-4.85), having a history of sexual behavior (OR=1.91, 95% CI: 1.09-3.35), accepting premarital sex (OR=1.36, 95% CI: 1.04-1.78), having a family history of tumors (OR=1.69, 95% CI: 1.28-2.23), monthly consumption level≥2 000 yuan (OR=1.50, 95% CI: 1.22-1.84), knowing about HPV vaccine (OR=1.75, 95% CI: 1.11-2.77), knowing that HPV vaccine is on the market (OR=1.71, 95% CI: 1.44-2.03), knowing that HPV infection is related to cervical cancer (OR=1.44, 95% CI: 1.15-1.81), having someone around who has received HPV vaccine (OR=2.23, 95% CI: 1.66-3.01), and having a high score in the cognition of HPV and its vaccine (OR=1.86, 95% CI: 1.32-2.62) were identified as promoting factors.

Conclusion

The willingness rate of Chinese college students to receive the HPV vaccine is relatively high, relevant epidemic prevention departments and health institutions should strengthen the professional popularization of HPV vaccine-related knowledge among college students, and try to improve the HPV vaccine vaccination service system and cervical cancer prevention and control service system.

Human papillomavirus vaccine  /  Vaccination willingness  /  College student  /  China  /  Influencing factors  /  Meta-analysis
Yue-lin WANG, Yun-lan JIANG, Le LI, Hong CHEN, Jing WANG, Meng-jie ZHANG, Xiao-yu BAI, Sen-lin WU. The current status and influencing factors of HPV vaccination willingness among college students in China: a systematic review and meta-analysis[J]. Modern Preventive Medicine, 2025 , 52 (18) : 3424 -3431 . DOI: 10.20043/j.cnki.MPM.202504095
Year 2025 volume 52 Issue 18
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doi: 10.20043/j.cnki.MPM.202504095
  • Receive Date:2025-04-06
  • Online Date:2026-02-10
  • Published:2025-09-25
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  • Received:2025-04-06
Affiliations
    College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China
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表12种不同金属材料的力学参数

Family
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Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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