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Detection of fishery anesthetics residues in commonly marketed fresh and live freshwater fish and shrimp, Shandong, 2021-2023
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Ying ZHU, Ling-yu CHAI, Chong-chong NIE, Rui JIA, Hai-yan HAN
Modern Preventive Medicine | 2025, 52(18) : 3337 - 3340
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Modern Preventive Medicine | 2025, 52(18): 3337-3340
Nutrition and Food Hygiene
Detection of fishery anesthetics residues in commonly marketed fresh and live freshwater fish and shrimp, Shandong, 2021-2023
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Ying ZHU, Ling-yu CHAI, Chong-chong NIE, Rui JIA, Hai-yan HAN
Affiliations
  • Jining Center for Disease Control and Prevention, Jining, Shandong 272000, China
Published: 2025-09-25 doi: 10.20043/j.cnki.MPM.202503476
Outline
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Objective

To investigate and to analyze the residue status of fishery anesthetics in commonly marketed fresh and live freshwater fish and shrimp in Shandong Province.

Methods

From 2021 to 2023, a total of 480 freshwater fish and shrimp were collected from 16 prefecture-level cities in Shandong Province, and the four anesthetics of eugenol, MS-222, diazepam, and oxazepam were detected by ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

Results

Among the four anesthetics, eugenol had the highest detection rate of 31.9% (153/480), followed by diazepam and oxazepam with detection rates of 6.7% (32/480) and 3.1% (15/480), and MS-222 was not detected. Eugenol had the highest detection rate and level of detection in grass carp, diazepam was detected only in fish and oxazepam was detected only in shrimp.

Conclusion

The primary fishery anesthetic detected in commonly marketed fresh and live freshwater fish and shrimp in Shandong Province is eugenol, with overall low residue levels.

Freshwater fish and shrimp  /  fishery anesthetics  /  Residue
Ying ZHU, Ling-yu CHAI, Chong-chong NIE, Rui JIA, Hai-yan HAN. Detection of fishery anesthetics residues in commonly marketed fresh and live freshwater fish and shrimp, Shandong, 2021-2023[J]. Modern Preventive Medicine, 2025 , 52 (18) : 3337 -3340 . DOI: 10.20043/j.cnki.MPM.202503476
Year 2025 volume 52 Issue 18
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doi: 10.20043/j.cnki.MPM.202503476
  • Receive Date:2025-03-25
  • Online Date:2026-02-10
  • Published:2025-09-25
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  • Received:2025-03-25
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    Jining Center for Disease Control and Prevention, Jining, Shandong 272000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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