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To explore the association ofbody mass index (BMI), body roundness index (BRI), waist circumference (WC), and waist hip ratio (WHR) with the risk of all-cause mortality in a community-based cohort.
This study was based on a prospective cohort study conducted in Pudong New Area. Obesity-related indicators were obtained at the baseline survey, mortality data was collectedduring the follow-up period.The associations between BMI, BRI, WC, WHR and the risk of all-cause mortality were assessed using cox proportional hazard model, restricted cubic spline (RCS) regression model, and receiver operator characteristic (ROC) curve.
A total of 9 448 participants was included in the analysis. The median follow-up time was 10.77 years, during which 987 deaths occurred,the all-cause mortality was 10.08/1 000 person-years.After multi-variable adjustment,the HR(95% CI) of elevated BRI, WC, and WHR were 1.07(1.01-1.14), 1.12(1.05-1.20), and 1.14(1.07-1.21), respectively.There were U-shaped dose-response relationship betweenBMI, BRI, WC and all-cause mortality; and alinear dose-response relationshipbetween WHR and all-cause mortality. BRI had the highest accuracy in predicting all-cause mortality, with the AUC of 0.62(95% CI=0.60-0.64).
Obesity is a significant risk factor for all-cause mortality, proper control of obesity and fat distribution can help reduce the risk of all-cause mortality.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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