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To investigate the association between the cardiometabolic index (CMI) and diabetes risk among hypertensive patients.
Utilizing health examination data from the National Basic Public Health Service Project in Jianye District, Nanjing (2019—2023), CMI was calculated basing on triglycerides, high-density lipoprotein cholesterol, waist circumference, and height. Diabetes was diagnosed according to the National Basic Diabetes Prevention and Management Guidelines (2022). Multivariable logistic regression models were applied to evaluate the association between CMI and diabetes risk, with odds ratios(ORs) and 95% confidence intervals(CIs) calculated. Restricted cubic spline analysis was used to explore the dose-response relationship. Subgroup analyses were performed to assess effect modifications.
This study included 56 760 hypertensive patients, with a final effective sample of 28 665 after excluding those with missing CMI-related indicators, of whom 7 535 had diabetes. Compared to those with lower CMI, hypertensive patients with higher CMI had significantly increased diabetes risk (P<0.001). Logistic analysis showed the highest CMI group (Q4) had a 40% higher diabetes risk than the lowest group (Q1) (OR=1.40, 95% CI: 1.30-1.52). Dose-response analysis revealed a nonlinear relationship (nonlinear P<0.001), indicating extreme CMI values might signal higher metabolic risks. Stratified analysis found a stronger association between CMI and diabetes risk in female hypertensive patients (OR=1.21, 95% CI: 1.16-1.27).
In Nanjing Jianye District residents, there is a significant positive correlation between CMI and diabetes risk in hypertensive patients, more pronounced in women. It is recommended to include CMI in metabolic risk assessment for community hypertensive patients, with a focus on personalized intervention for abdominal obesity and dyslipidemia in women.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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