To analyze the temporal trends and driving factors of the burden of leukemia attributable to smoking in China from 1990 to 2023, and to provide evidence for prevention and control strategies.
Based on the Global Burden of Disease Study 2023 database, data on leukemia deaths and disability-adjusted life years (DALYs) attributable to smoking in China were extracted. The Joinpoint regression model was used to analyze the temporal trends of standardized rates. Decomposition analysis was employed to explore the impacts of population growth, aging, and epidemiological changes on the disease burden.
From 1990 to 2023, the number of leukemia deaths attributable to smoking in China increased from 4 200 to 8 200 (an increase of 96.82%), and DALYs increased from 118 300 to 203 600 person-years (an increase of 72.13%). The age-standardized mortality rate (ASMR) and age-standardized DALY rate (ASDR) showed downward trends (with average annual percent changes of -0.97% and -1.13%, respectively, P<0.001). Decomposition analysis indicated that population growth and aging were the main driving forces for the increase in the absolute value of the disease burden.
Although the age-standardized burden of leukemia attributable to smoking in China showed a declining trend from 1990 to 2023, the absolute burden continued to increase under the influence of factors such as population aging, and significant sex disparities were observed. Males and older adults should be prioritized in prevention and control efforts, and tobacco control interventions should be further strengthened to curb the growing burden.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |