Full
Outline
To understand the current status of chronic comorbidities and impaired activities of daily living in elderly OP patients, explore the association between different comorbidity combinations and daily ADL, and provide theoretical basis for improving the quality of life of elderly OP comorbidities.
In April 2025, a stratified cluster random sampling method was used to select research subjects from two townships in Yanchi County, Ningxia, to conduct a questionnaire survey and measure bone density. Obtain association rules for chronic disease combinations in elderly OP patients through association rules, and use binary logistic regression to analyze the magnitude of the association between comorbidities in elderly OP and ADL impairment.
This study included 685 elderly OP patients, with a chronic disease comorbidity rate of 66.72%. The rates of BADL, IADL, and ADL impairment were 10.66%, 11.97%, and 16.79%, respectively. Through the Apriori algorithm, a total of 12 association rules were identified, with “hypertension and osteoporosis” being the most common comorbidity among all combinations (47.445%). Single factor logistic regression analysis shows that the comorbidity combination of “hypertension, lumbar disc disease, and osteoporosis” was significantly associated with increased impairment in BADL and ADL compared to elderly OP patients ［(OR=3.69, 95%CI：1.80-7.55), (OR=3.25, 95%CI：1.69-6.25)］. The comorbidity combination of “hypertension, heart disease, and osteoporosis” was associated with a higher likelihood of impaired IADL (OR=3.73, 95%CI：2.08-6.69). The results of multiple logistic regression showed that compared with elderly OP patients, the comorbid combination of “lumbar disc disease and osteoporosis” increased the likelihood of impaired BADL and ADL ［(OR=4.27, 95%CI：2.28-7.99), (OR=3.62, 95%CI：2.06-6.38)］, while the “hypertension, heart disease, and osteoporosis” combination was associated with a higher likelihood of IADL impairment (OR=3.02, 95%CI：1.57-5.80).
Elderly OP patients have impaired activities of daily living, and hypertension plays an important comorbidity center in elderly OP patients. Multiple comorbidity combinations significantly increase the risk of ADL impairment. The healthcare system should focus on the elderly population with comorbidities, develop effective long-term care policies for different comorbidities, and enhance the elderly’s sense of health and quality of life.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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