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Outline
To understand the current status and influencing factors of frailty occurrence among middle-aged and elderly patients with H-type hypertension, and to construct a predictive model for frailty risk in this population.
Based on univariate and binary logistic regression analyses, screen for independent influencing factors, construct a risk prediction model for the occurrence of frailty in H-type hypertension, and create a visual nomogram. Finally, evaluate the predictive value of the risk prediction model using the H-L goodness-of-fit test, ROC curve, and calibration curve.
This study included a total of 783 middle-aged and elderly patients with H-type hypertension, among whom 207 developed frailty (26.4%). Binary logistic regression analysis showed that age (OR=1.055, 95% CI: 1.032-1.079), education level (OR=0.656, 95% CI: 0.495-0.870), blood urea nitrogen (OR=1.215, 95% CI: 1.092-1.352), and high-density lipoprotein (OR=0.475, 95% CI: 0.273-0.826) were independent factors influencing the development of frailty in middle-aged and elderly patients with H-type hypertension. A logistic regression prediction model was constructed based on these influencing factors, with the Hosmer-Lemeshow goodness-of-fit test yielding a P-value of 0.836. The area under the ROC curve (AUC) was 0.733, 95% CI=0.694-0.771, indicating that the model has good discriminative ability. The calibration curve showed a high consistency between the predicted values and the observed values.
The incidence of frailty among middle-aged and elderly patients with H-type hypertension remains at a relatively high level. A risk prediction model based on these factors has certain predictive value for the occurrence of frailty in patients with H-type hypertension.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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