Analyzing and evaluating the association between estimated glucose disposal rate (eGDR) and metabolic syndrome (MetS) among coal miners.
A cross-sectional study design was employed, with 8 102 employees from coal mining groups who underwent occupational health examinations in 2023 serving as the study subjects. Individual eGDR values were calculated based on waist circumference, hypertension status, and glycated hemoglobin levels, with MetS defined according to the criteria outlined in the Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020 Edition). Unconditional logistic regression models and restricted cubic spline (RCS) models were employed to investigate the association and dose-response relationship between eGDR and MetS, whilst also analyzing the interaction between eGDR and occupational factors on MetS.
The mean age of enrolled employees was (48.7±5.4) years, with 2 932 individuals diagnosed with MetS (prevalence: 36.1%). Fully adjusted unconditional logistic regression analysis revealed that each standard deviation increases in eGDR (SD=2.23) reduced the risk of MetS to 0.52. The high eGDR group exhibited significantly lower MetS risk than the low eGDR group (OR=0.01), with no significant evidence of occupational factor interaction. RCS modeling revealed a strong nonlinear negative dose-response relationship between eGDR and MetS prevalence (P<0.001).
Among coal miners, eGDR exhibits a significant association with Mets, presenting a non-linear negative dose-response relationship, and no occupational factor interactions have been identified.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |