Full
Outline
To investigate the association between dynapenic abdominal obesity (characterized by reduced handgrip strength combined with abdominal obesity) and the risk ofdiabetes in middle-aged and older Chinese adults.
Using data from the China Health and Retirement Longitudinal Study (China Health and Retirement Longitudinal Study,CHARLS) 2011-2015, 4 556 participants aged ≥45 years without diabetes at baseline were included. Based on handgrip strength (men <28 kg, women <18 kg) and waist circumference (men ≥90 cm, women ≥85 cm), participants were categorized into four groups:non-dynapenic/non-abdominal obesity (ND/NAO),non-dynapenic/abdominal obesity (ND/AO),dynapenic/non-abdominal obesity (D/NAO), and dynapenic abdominal obesity (D/AO).Cox proportional hazards models were employed to analyze the association between each group and diabetes risk, and subgroup analysis was conducted to explore the association between dynapenic abdominal obesity and the risk of diabetes onset under different groupings.
After a mean follow-up of 4 years, 495 new cases of diabetes mellitus were recorded，representing an incidence rate of 10.9% and an incidence density of 27.2 per 1 000 person-years. Following multivariable adjustment, compared with the ND/NAO group, the ND/AO group exhibited a 71% increased risk of diabetes onset (HR=1.709, 95% CI: 1.395-2.095), while the D/AO group showed a 123% increased risk (HR=2.226, 95% CI: 1.472-3.366). No significant difference was observed in the D/NAO group (P>0.05), with subgroup analyses yielding consistent results.
Dynapenic abdominal obesity significantly increases the risk of diabetes among middle-aged and older Chinese adults,with a higher risk than abdominal obesity alone.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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