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Correlation of C-reactive protein-albumin-lymphocyte index with rheumatoid arthritis: a cross-sectional NHANES-based study
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Yi-hang DING1, Lu-ying WANG1, Si-yi LU1, Xiu-juan HOU2
Modern Preventive Medicine | 2025, 52(24) : 4584 - 4590
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Modern Preventive Medicine | 2025, 52(24): 4584-4590
• Clinical Medicine and Prevention •
Correlation of C-reactive protein-albumin-lymphocyte index with rheumatoid arthritis: a cross-sectional NHANES-based study
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Yi-hang DING1, Lu-ying WANG1, Si-yi LU1, Xiu-juan HOU2
Affiliations
  • School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
Published: 2025-12-25 doi: 10.20043/j.cnki.MPM.202507178
Outline
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Objective

To analyze the value of the C-reactive protein-albumin-lymphocyte (CALLY) index as a predictor of rheumatoid arthritis (RA) risk in the general population.

Methods

Data from 9 791 participants in the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018 were included. The CALLY index was calculated, and multiple models were used to investigate and evaluate the association between CALLY and RA.

Results

Compared to the lowest quartile (Q1) of the CALLY index, the odds ratio (OR) for RA were 0.71 (95% CI: 0.57-0.89) for Q2, 0.63 (95% CI: 0.49-0.80) for Q3, and 0.49 (95% CI: 0.37-0.65) for Q4. A significant non-linear relationship existed between the CALLY index and RA (P<0.001).

Conclusion

The CALLY index demonstrates a significant negative correlation with the risk of rheumatoid arthritis.

Rheumatoid arthritis  /  CALLY  /  Inflammation  /  NHANES
丁一航, 王露盈, 卢斯仪, 侯秀娟. C反应蛋白-白蛋白-淋巴细胞指数与类风湿关节炎的相关性研究:基于NHANES的横断面研究. 现代预防医学, 2025 , 52 (24) : 4584 -4590 . DOI: 10.20043/j.cnki.MPM.202507178
Yi-hang DING, Lu-ying WANG, Si-yi LU, Xiu-juan HOU. Correlation of C-reactive protein-albumin-lymphocyte index with rheumatoid arthritis: a cross-sectional NHANES-based study[J]. Modern Preventive Medicine, 2025 , 52 (24) : 4584 -4590 . DOI: 10.20043/j.cnki.MPM.202507178
Year 2025 volume 52 Issue 24
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doi: 10.20043/j.cnki.MPM.202507178
  • Receive Date:2025-07-11
  • Online Date:2026-11-02
  • Published:2025-12-25
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  • Received:2025-07-11
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    School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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