Full
Outline
To analyze the disease burden of adverse effects of medical treatment (AEMT) among Chinese residents from 1990 to 2021, thereby providing a reference for the health department to formulate patient safety policies.
The mortality,incidence, disability-adjusted life years(DALYs) data of AEMT and regional sampling data were extracted from the Global Health Data Exchange and the National Health Service and Quality Safety Report. The trends and effects were analyzed using the Joinpoint-jump model and Age-period-cohort model, and regional differences were analyzed by hierarchical clustering.
The overall trends of incidence, mortality and DALYs of AEMT from 1990 to 2021 gradually declined. The AAPCs were -1.28%, -5.59% and -6.47%,respectively. The comparability ratio (CR) values of overall incidence and mortality were 0.99 and 1.02, respectively. The number of male AEMT cases decreased from 208 100 to 170 700, while the number of female cases dropped from 224 100 to 172 700. The risk of death was the highest among residents over 95 years old (RR=10.55, 95% CI: 5.93-18.75), which was 2.27 times that of residents aged 0-4 years (RR=4.65, 95% CI: 3.83-5.64). The risk of DALYs increased among those aged 0-4 years (RR=8.56, 95% CI: 5.83-12.55),which was 14.57 times that of residents aged 50-54 years (RR=0.59, 95% CI: 0.47-0.73). In 2022, the regional clustering of AEMT reported per hospital was categorized into 2 clusters, Zhejiang (632.16 cases per hospital) belonged to the high-high cluster, while Tibet (49.23 cases per hospital) belonged to the low-low cluster.
The burden of AEMT in China is gradually decreasing. It is necessary to consider the prevention and control strategies for key populations, including those aged 0-4 years and above 80 years, as well as remote areas, leverage artificial intelligence to reduce AEMT, and promote the development of medical safety to a higher level.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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