Full
Outline
To describe the spatio-temporal distribution of the incidence of colorectal cancer(CRC) in China and provide epidemiological evidence for prevention and treatment.
Based on the data of CRC incidence in the Chinese Cancer Registry Annual Report from 2008 to 2021, the temporal trend was analyzed by the Joinpoint regression model, the spatial autocorrelation analysis was conducted to examine spatial distribution patterns, and the influencing factors were analyzed by the age-period-cohort model.
From 2005 to 2018, the age standardized incidence rate (ASIR) of CRC in China was 23.77/100 000, showing a downward trend (AAPC=-1.1%). The ASIR of males and urban areas was higher than that of females and rural areas. The incidence of CRC exhibited a spatial clustering pattern in the eastern region. The eastern region was identified as a high-risk hotspot area. The age effect indicated that the risk of developing CRC increased with age. Time effect showed that the incidence of CRC in China was on the decline, but the incidence of CRC in rural areas was on the rise. In terms of the cohort effect, the population born between 1925 and 1929 had the highest risk of developing CRC.
From 2005 to 2018, the ASIR of CRC had decreased, but there were population and regional differences. The eastern region had been identified as a hotspot area.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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