To explore the status quo of disease perception stress of primary infertility patients in childbearing age, and analyze the relationship between it and couples’ support and coping.

A total of 798 primary infertility patients of childbearing age admitted to the hospital from January 2023 to January 2025 were selected for the study. The General information Questionnaire, the Simplified version of the Disease Perception Questionnaire (BIPQ) scale, the Marital Support Coping (DCI) Scale, and the Stigma Scale for Female Infertility Patients (ISS) were used for the investigation.

The BIPQ score of primary infertility in childbearing age was (55.67±6.43), and the pressure of disease perception was high. Pearson correlation analysis showed that BIPQ score was negatively correlated with DCI score (r=-0.243) and positively correlated with ISS score (r=0.309) (P<0.05). The results of multiple linear regression analysis showed that the higher the age, the higher the stress of patients (B=2.996, 95% CI: 2.349-3.642), the higher the educational level, the lower the pressure (B=-2.149,95% CI: -2.831--1.468), the higher the pressure of patients who think that childbirth is the most important thing in life (B=4.969, 95% CI:4.277-5.661), and the worse the relationship between husband and wife, the higher the pressure (B=2.396, 95% CI: 1.692-3.100), the higher the DCI score, the lower the stress (B=-0.044, 95% CI:-0.065--0.022), and the higher the ISS score, the higher the stress(B=0.077, 95% CI:0.055-0.099) (P<0.05).

The primary infertility patients in childbearing age have a high level of disease perception pressure, so we should focus on those who are older, have low educational level, have a traditional concept of fertility, have poor relationship between husband and wife and have a high sense of shame, and formulate corresponding intervention strategies to improve the mental health level of patients.