Full
Outline
To investigate the incidence of hypertension（HTN）among patients with type 2 diabetes mellitus（T2DM）under standardized management in Hotan City, and to explore its associated risk factors.
A retrospective cohort study was conducted on 1 053 T2DM patients without baseline hypertension who underwent continuous health examinations from 2016 to 2023 in Hotan, Xinjiang. With new-onset hypertension as the endpoint event, their physical examination data were collected and analyzed. A multivariate Cox proportional hazards regression model was employed to analyze the relevant influencing factors.
The average follow-up period was 4.29 years. The incidence density of hypertension among T2DM patients under standardized management was 134.66/1 000 person-years（95% CI: 124.18-145.80）, with a 5-year cumulative incidence rate of 48.81%（95% CI: 45.79-51.83）.The Cox regression analysis indicated that age ≥60 years（HR=3.41, 95% CI: 2.59-4.49）, retirement（HR=1.60, 95% CI: 1.07-2.41）, increased waist circumference（HR=1.01, 95% CI: 1.00-1.02）, and positive urinary protein（HR=1.92, 95% CI: 1.05-3.51）were independent risk factors. Male gender was a protective factor（HR=0.81, 95% CI: 0.68-0.96）. A non-linear, J-shaped relationship was observed between baseline systolic blood pressure and the risk of hypertension, with the risk significantly increasing when SBP exceeded approximately 115 mmHg.
The risk of hypertension remains high among T2DM patients under standardized management in Hotan City. It is imperative to strengthen risk assessment and management for high-risk populations, including the elderly, females, retirees, individuals with abdominal obesity, and those with positive urinary protein. For T2DM patients with elevated systolic blood pressure, intensive, full-course blood pressure monitoring and management are necessary to achieve early identification and effective control of hypertension.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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