PDF
Full
Outline
Objective To investigate the association between the dietary index for gut microbiota (DI-GM) and metabolic syndrome (MetS), thereby providing a theoretical basis for preventing MetS through dietary modulation of the gut microbiome. Methods Data from 17 558 adults participating in the 2007—2018 U.S. National Health and Nutrition Examination Survey (NHANES) were analyzed, with MetS determined according to the NCEP ATP III criteria. The DI-GM score was constructed based on 14 food items or nutrients obtained from two 24 hour dietary recalls. Logistic regression models and restricted cubic spline (RCS) analysis were used to evaluate the relationship between DI-GM and MetS, and subgroup as well as sensitivity analyses were conducted. Results In the fully adjusted model, the risk of MetS decreased with increasing DI-GM scores (OR=0.94, 95% CI: 0.91-0.98). Specifically, individuals in the highest DI-GM quartile (Q4) had an 18% lower risk of MetS than those in the lowest quartile (OR=0.82, 95% CI: 0.72-0.95). RCS analysis indicated a linear inverse dose-response relationship between DI-GM and MetS (P for nonlinear=0.185). Subgroup analyses showed the inverse association was stronger in females, non-Hispanic Black individuals, and those with higher education levels(P for interaction<0.05). Sensitivity analyses confirmed the stability of the results(OR=0.94, 95% CI: 0.90-0.98). Conclusion This study demonstrates that maintaining a diet favorable to gut microbiota health can reduce the risk of MetS. These findings suggest that improving dietary patterns to modulate the gut microbiome may offer a novel strategy for the prevention and management of MetS.
PDF
70
29
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62199257
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
