Full
Outline
To explore the chain mediating role of activities of daily living and physical pain between chronic diseases and depressive symptoms in the elderly, and to provide new perspectives and intervention strategies for the prevention and alleviation of depressive symptoms in the elderly.
Based on the data of the 2020 China Health and Retirement Longitudinal Survey (CHARLS), the chain mediation model was constructed with the help of the PROCESS 4.1 program, and 5 000 repeated samplings were conducted using the Bootstrap method to verify the mediation variables.
A total of 7 505 elderly people aged 60 and above were included. Chronic diseases in the elderly were positively correlated with depressive symptoms (r=0.284, P<0.01), activities of daily living (r=0.265, P<0.01), and physical pain (r=0.379, P<0.01). The mediation test showed that chronic diseases in the elderly had a direct effect on depressive symptoms (β=0.451, 95% CI: 0.384-0.520), and activities of daily living (β=0.302, 95% CI: 0.280-0.324) and pain (β=0.522, 95% CI: 0.486-0.558) had significant individual mediating effects between the two. The chain mediating effect of activities of daily living and physical pain between the number of chronic diseases and depressive symptoms was significant (β=0.036, 95% CI: 0.029-0.044), and the total mediating effect and chain mediating effect accounted for 48.46% and 4.10% of the total effect, respectively.
Chronic diseases are significantly associated with depressive symptoms in the elderly. Activities of daily living and physical pain have a chain mediating effect between chronic diseases and depressive symptoms in the elderly. Emphasis should be placed on the synergistic effect of pain management and functional rehabilitation in the elderly. Early prevention should be carried out to reduce depressive symptoms in patients with chronic diseases and improve the quality of life of the elderly.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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