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The mediating role of psychological resilience between childhood trauma and the severity of depressive disorder and its latent profile analysis
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Li-yuan GUO1, 2, Wang-tao LI1, 3, Yi-ying HU4, Li-yuan LUO5, Lan-ying LIU1, 3
Modern Preventive Medicine | 2025, 52(23) : 4315 - 4319
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Modern Preventive Medicine | 2025, 52(23): 4315-4319
• Child and Adolescent Health, Maternal and Child Health •
The mediating role of psychological resilience between childhood trauma and the severity of depressive disorder and its latent profile analysis
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Li-yuan GUO1, 2, Wang-tao LI1, 3, Yi-ying HU4, Li-yuan LUO5, Lan-ying LIU1, 3
Affiliations
  • Department of Traditional Chinese Medicine, Mental Health Center, Shanghai Jiao Tong University School of Medicine,Shanghai 200030, China
Published: 2025-12-10 doi: 10.20043/j.cnki.MPM.202411381
Outline
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Objective

Exploring the mediating role of psychological resilience in the relationship between childhood trauma and the severity of depression among individuals with depressive disorder, and to identify subtypes of depressive disorder by latent profile analysis and analyze the related factors among subtypes.

Methods

General information questionnaire, Hamilton Depression Rating Scale (HAMD), Childhood Trauma Questionnaire (CTQ-SF) and Connor-Davidson Resilience Scale (CD-RISC) were used to investigate 360 patients with depressive disorder in outpatient department and ward of Traditional Chinese Medicine Department of Shanghai Mental Health Center.

Results

HAMD was positively correlated with CTQ-SF and the scores of all dimensions (P<0.01), and negatively correlated with CD-RISC and the scores of all dimensions (P<0.01). There was a significant negative correlation between CTQ-SF and CD-RISC (P<0.01). The mediation effect test indicated that childhood trauma had a significant direct predictive effect on the severity of depressive disorder (β=0.079, t=12.984, P<0.001). After adding psychological resilience as a mediating variable, the direct predictive effect of childhood trauma on the severity of depressive disorder remained significant (β=0.050, t=2.636, P<0.01). Latent profile analysis showed that patients with depressive disorder could be classified into low-trauma-high-resilience depressive disorder (72.8%) and high-trauma-low-resilience depressive disorder (27.2%). Gender, age, marital status and educational background were the predictors of latent profile classification(P<0.05).

Conclusion

The severity of depression is correlated with childhood trauma and psychological resilience, and childhood trauma can effectively predict the severity of depression. Individuals with higher levels of childhood trauma and lower levels of psychological resilience are more prone to developing depressive disorder. It is recommended to enhance individual psychological resilience to reduce the occurrence of depressive disorder.

Depressive disorder  /  Childhood trauma  /  Psychological resilience  /  Mediating effect  /  Latent profile analysis
郭励园, 厉汪涛, 胡奕颖, 骆利元, 刘兰英. 心理弹性在童年创伤与抑郁严重程度间的中介作用及其潜在剖面分析. 现代预防医学, 2025 , 52 (23) : 4315 -4319 . DOI: 10.20043/j.cnki.MPM.202411381
Li-yuan GUO, Wang-tao LI, Yi-ying HU, Li-yuan LUO, Lan-ying LIU. The mediating role of psychological resilience between childhood trauma and the severity of depressive disorder and its latent profile analysis[J]. Modern Preventive Medicine, 2025 , 52 (23) : 4315 -4319 . DOI: 10.20043/j.cnki.MPM.202411381
Year 2025 volume 52 Issue 23
39
20
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doi: 10.20043/j.cnki.MPM.202411381
  • Receive Date:2024-11-28
  • Online Date:2026-11-02
  • Published:2025-12-10
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  • Received:2024-11-28
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    Department of Traditional Chinese Medicine, Mental Health Center, Shanghai Jiao Tong University School of Medicine,Shanghai 200030, China
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小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
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