To systematically evaluate the factors influencing the willingness to accept HIV post-exposure prophylaxis (PEP) among men who have sex with men (MSM) in China.
Studies related to the willingness to accept HIV PEP among MSM published before September 5, 2024, were searched in PubMed, Web of Science, The Cochrane Library, EM base, China National Knowledge Infrastructure (CNKI), Wan fang, VIP, and CBM databases. Meta-analysis of the included factors was conducted using Rev Man 5.3 software.
A total of 26 studies were included, with 31 600 participants, and 20 influencing factors were extracted. The results of the meta-analysis indicated that factors promoting the willingness to accept HIV PEP included: age ≤ 30 years (OR=1.65, 95%CI:1.31-2.07), monthly income of 5 000-10 000 yuan (OR=1.96, 95%CI: 1.51-2.55), monthly income > 10 000 yuan (OR=1.98, 95%CI:1.03-3.80), having an HIV-positive sexual partner (OR=2.47, 95%CI: 1.21-5.05), multiple sexual partners (OR=2.51, 95%CI: 1.90-3.32), online sexual partners (OR=2.03, 95%CI: 1.55-2.65), awareness of HIV-related knowledge (OR=2.33, 95%CI: 1.81-3.00), awareness of PEP-related knowledge (OR=2.17, 95%CI: 1.33-3.54), having consulted about PEP (OR=26.09, 95%CI: 5.34-127.41), use of recreational drugs (OR=2.01, 95%CI: 1.18-3.42), condom use (OR=2.10, 95%CI: 1.66-2.66), HIV testing at least twice a year (OR=2.33, 95%CI: 1.80-3.02), sexually transmitted infections (OR=1.93, 95%CI: 1.52-2.45), commercial sex work (OR=3.21, 95%CI:1.95-5.30), and peer education (OR=1.60, 95%CI: 1.23-2.08). The factor hindering willingness was identified as being gay (OR=0.34,95%CI: 0.23-0.49).
The factors influencing the willingness to accept HIV PEP among MSM in China are various and complex. Future efforts should focus on enhancing the promotion and dissemination of knowledge related to HIV and PEP to reduce the incidence of HIV within the MSM population.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |