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Meta-analysis of factors influencing willingness to accept HIV post-exposure prophylaxis among Chinese men who have sex with men
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Yan HE1, Xin CHU2, Na-na LI1, Min-yao ZHENG1, Jia RAO3
Modern Preventive Medicine | 2025, 52(1) : 167 - 173
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Modern Preventive Medicine | 2025, 52(1): 167-173
• Disease Control and Prevention •
Meta-analysis of factors influencing willingness to accept HIV post-exposure prophylaxis among Chinese men who have sex with men
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Yan HE1, Xin CHU2, Na-na LI1, Min-yao ZHENG1, Jia RAO3
Affiliations
  • School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610103, China
Published: 2025-01-10 doi: 10.20043/j.cnki.MPM.202409285
Outline
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Objective

To systematically evaluate the factors influencing the willingness to accept HIV post-exposure prophylaxis (PEP) among men who have sex with men (MSM) in China.

Methods

Studies related to the willingness to accept HIV PEP among MSM published before September 5, 2024, were searched in PubMed, Web of Science, The Cochrane Library, EM base, China National Knowledge Infrastructure (CNKI), Wan fang, VIP, and CBM databases. Meta-analysis of the included factors was conducted using Rev Man 5.3 software.

Results

A total of 26 studies were included, with 31 600 participants, and 20 influencing factors were extracted. The results of the meta-analysis indicated that factors promoting the willingness to accept HIV PEP included: age ≤ 30 years (OR=1.65, 95%CI:1.31-2.07), monthly income of 5 000-10 000 yuan (OR=1.96, 95%CI: 1.51-2.55), monthly income > 10 000 yuan (OR=1.98, 95%CI:1.03-3.80), having an HIV-positive sexual partner (OR=2.47, 95%CI: 1.21-5.05), multiple sexual partners (OR=2.51, 95%CI: 1.90-3.32), online sexual partners (OR=2.03, 95%CI: 1.55-2.65), awareness of HIV-related knowledge (OR=2.33, 95%CI: 1.81-3.00), awareness of PEP-related knowledge (OR=2.17, 95%CI: 1.33-3.54), having consulted about PEP (OR=26.09, 95%CI: 5.34-127.41), use of recreational drugs (OR=2.01, 95%CI: 1.18-3.42), condom use (OR=2.10, 95%CI: 1.66-2.66), HIV testing at least twice a year (OR=2.33, 95%CI: 1.80-3.02), sexually transmitted infections (OR=1.93, 95%CI: 1.52-2.45), commercial sex work (OR=3.21, 95%CI:1.95-5.30), and peer education (OR=1.60, 95%CI: 1.23-2.08). The factor hindering willingness was identified as being gay (OR=0.34,95%CI: 0.23-0.49).

Conclusion

The factors influencing the willingness to accept HIV PEP among MSM in China are various and complex. Future efforts should focus on enhancing the promotion and dissemination of knowledge related to HIV and PEP to reduce the incidence of HIV within the MSM population.

Men who have sex with men  /  Post exposure prophylaxis  /  Influencing factors  /  China  /  Meta-analysis
何艳, 楚鑫, 李娜娜, 郑敏瑶, 饶佳. 中国男男性行为者HIV暴露后预防用药接受意愿相关因素的Meta分析. 现代预防医学, 2025 , 52 (1) : 167 -173 . DOI: 10.20043/j.cnki.MPM.202409285
Yan HE, Xin CHU, Na-na LI, Min-yao ZHENG, Jia RAO. Meta-analysis of factors influencing willingness to accept HIV post-exposure prophylaxis among Chinese men who have sex with men[J]. Modern Preventive Medicine, 2025 , 52 (1) : 167 -173 . DOI: 10.20043/j.cnki.MPM.202409285
Year 2025 volume 52 Issue 1
54
26
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doi: 10.20043/j.cnki.MPM.202409285
  • Receive Date:2024-09-15
  • Online Date:2026-10-29
  • Published:2025-01-10
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  • Received:2024-09-15
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    School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610103, China
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表12种不同金属材料的力学参数
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小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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