Objective To establish a method for benzo[α]pyrenedetermination in prepared Radix Rehmanniae by molecularly imprintedsolid phase extraction coupled with ratio fluorescence detection. Methods The molecularly imprinted polymers (BaP-MMIPs) were prepared bysol-gel method using dendritic-grafting magnetic nanoparticle as thesupporting material and benzo $\left\lbrack \alpha \right\rbrack$ pyreneas the template. Benzo[ $\alpha$ ]pyrene in the prepared sample wasseparated and enriched by BaP-MMIPs as dispersive SPE materials, and wasdetected by ratio fluorescence determination. The calibration curve wasobtained by measuring the fluorescence intensity ratios $\left({{\mathrm{I}}_{436}/{\mathrm{I}}_{604}}\right)$ of benzo $\left\lbrack \alpha\right\rbrack$ pyrene in different concentrations. ResultsBaP-MMIPs showed remarkable selectivity, high efficiency and stable,which were successful applied as solid phase extraction materials forthe trace benzo[a]pyrene determination in prepared Radix Rehmanniae.Good linearity was achieved in range of 0.14~3.0 $\mu \mathrm{g}/\mathrm{{mL}}$ . The LOD was ${80}\mathrm{{ng}}/\mathrm{{mL}}\left({\mathrm{S}/\mathrm{N}=3}\right)$ and LOQ was ${112.5}\mathrm{{ng}}/\mathrm{{mL}}\left({\mathrm{S}/\mathrm{N}={10}}\right)$ . The average recoveries of benzo $\left\lbrack \alpha \right\rbrack$ pyrenewere 89.5%-106.8% with the RSD≤3.6%. Conclusion The method is accurate,selective, high sensitive, reproducible, economical, simple and fast.The research has profound significance for the benzo[a]pyrene monitoringin Traditional Chinese Medicine.

With the increasing demand of laboratory teaching and scientific research in colleges and universities, higher requirements are put forward for laboratory safety education, which is also an important content to ensure the safety of teachers and students, great importance must be attached to it. In view of this, colleges and universities should pay attention to laboratory culture, actively establish a safety education system, do a good job of top-level design, establish a sound evaluation mechanism, and gradually optimize educational methods and methods, and then build an integrated safety culture and education system.

The re evaluation of qualification recognition capability is a capability confirmation work that inspection and testing institutions need to carry out every six years. The new version of the "Criteria for Qualification Recognition and Review of Inspection and Testing Institutions" has been officially implemented since December 1, 2023. This article mainly elaborates on how to efficiently pass the qualification recognition re evaluation work of inspection and testing institutions under the requirements of the new criteria. Taking a certain inspection and testing institution in Beijing as an example, this article briefly introduces the entire process of re evaluation, including organization preparation, online reporting, on-site audit, later rectification, and evidence collection. It provides a detailed analysis of the entire process of re evaluation and points out the precautions to be taken when preparing application materials for re evaluation. This provides a reference for the qualification recognition re evaluation application and related work of inspection and testing institutions.

With the application of surveying and mapping technology in land management, urban planning, resources exploration, environmental protection, disaster prevention and other fields in our country, the demand for surveying and mapping talents is strong, and the construction and management of surveying and mapping engineering laboratories in colleges and universities play an increasingly prominent role in personnel training. At present, the phenomenon of insufficient area of surveying and mapping engineering laboratories in colleges and universities, the updating and maintenance of instruments and equipment are not timely, and the management measures are not in place is more prominent. On the basis of analyzing the existing problems, this paper explores how to strengthen the scientific management of laboratory from the aspects of marking, placing, registration management, maintenance and repair of instruments and equipment.

There are problems with insufficient resource utilization, traditional experimental teaching content, and limited scientific research in experimental teaching laboratories and scientific research laboratories in universities. Opening up laboratories is the main way to improve the utilization of laboratory resources. Opening up laboratories is beneficial for enhancing students' innovative thinking and research abilities, promoting scientific research achievements among teachers and students, improving the utilization of laboratory resources, solving laboratory management problems, and promoting the implementation of industry university research work. This paper takes experimental teaching laboratories and scientific research laboratories in universities as research objects, elaborates on the problems of laboratory opening, analyzes the measures that should be taken for laboratory opening, and proposes the mechanism for opening experimental teaching laboratories and scientific research laboratories in universities.

The convergence of laboratory testing standardization and automation technologies has had a profound impact on scientific research and industrial applications. Standardization provides a framework for consistency and comparability, while automated systems improve experimental efficiency and reliability of results. This article will explore the importance of standardization of laboratory testing and its integration with automation technology, as well as the importance of compliance with standards for automated systems.

New requirements have been put forward for biosafety in the new era, and it is also listed as a top priority. Medical universities are the cradle of medical talents. Microbiology, as an important subject in basic medicine which combine the theory and practice. Based on the biosafety problems existing in microbiology teaching laboratories, it is extremely urgent to optimization. Through analyzing the current situation of microbiology teaching laboratory, this article mainly discusses the current situation and optimization of microbiology teaching laboratories. In line with student-centered teaching conception, contains the safety awareness of teachers and students, laboratory safety management, and existing safety risks, so as to improve the scientific and specification of microbiology teaching laboratories.

Safety is the basic guarantee for university laboratories to carry out teaching and research. The dual prevention mechanism with risk classification control and hidden danger investigation and management as the core can effectively curb the occurrence of laboratory safety accidents. This paper describes the four stages of building a dual prevention mechanism, and uses the operating condition risk assessment method (LEC) to evaluate and grade laboratory risks, moving the threshold of laboratory risk management and control to the risk point classification management and control, and building a solid laboratory safety defense line.

Smart laboratories play an important role in scientific research and production, however, they also face safety risks and management challenges. Building a smart laboratory safety management platform system can help laboratory managers comprehensively manage laboratory safety risks. In order to effectively manage the safety issues of smart laboratories, this study aims to build a comprehensive smart laboratory safety management platform system. By formulating the use of inspection equipment, the management of hazardous chemicals in the laboratory, the laboratory environment monitoring, and ensuring capital investment, a laboratory safety funding guarantee system is built. Through innovative applications of Internet of Things technology and other measures, the functions of the smart laboratory safety management platform system are realized, so that the safety and management efficiency of the laboratory are improved.

In response to the issues of inconsistent safety risk management standards, specialized level of safety management, and differentiated control in university laboratories, based on the concept of "full staff education, full process education, and all-round education", this paper proposes the use of information technology to promote laboratory safety classification and grading management measures. Multiple methods such as quantitative, qualitative, or comprehensive evaluation are used to evaluate the degree of risk that may be caused by hazards. Based on the practice of integrating the "Three Comprehensive Education" into the laboratory culture education system of our university, explore the information management mode of safety classification and classification in university laboratories.