Objective To compare the role of enzyme-linkedimmunosorbent assay and toluidine red unheated serum test in thediagnosis of syphilis. Methods 78 suspected syphilis patients in ourhospital were analyzed from January 1st, 2023 to December 31st, 2023,enzyme linked immunosorbent assay and toluidine red unheated serum testwere performed on all patients, and the testing procedures were strictlyfollowed according to the instructions. Compare the diagnosticsensitivity, specificity, and accuracy of enzyme-linked immunosorbentassay (ELISA) and toluidine red unheated serum test based on the resultsof syphilis Treponema pallidum gelatin particle agglutination test.Results The sensitivity, specificity, and accuracy of the enzyme-linkedimmunosorbent assay were 93.24%, 75%, and 92.31%, respectively. Thesensitivity, specificity, and accuracy of the toluene red unheated serumtest were 82.43%, 50%, and 80.77%, respectively. The toluene redunheated serum test was lower than the enzyme-linked immunosorbentassay, with a difference of $P<{0.05}$ . Conclusion Enzyme linked immunosorbent assay(ELISA) has higher sensitivity and accuracy in syphilis testing comparedto the non heated serum test with toluidine red, and is worthy ofattention and promotion.

The article delves into real-time data processing methods for monitoring tool wear in computer numerical control (CNC) machine tools, with the aim of improving the overall accuracy of the tool monitoring system. The article also systematically reviews several mainstream data processing methods, including power spectrum analysis, wavelet transform, artificial neural network technology, and multi-sensor information fusion technology. Although these methods have their own advantages and disadvantages, a single method often fails to achieve ideal results when dealing with data in complex and changing processing environments. To overcome this challenge, this paper proposes a multi-sensor information fusion data processing method based on hybrid intelligent algorithms

Scientific research and experimental teaching are the main functions of university laboratory. Therefore, university laboratory plays an important role in personnel training and scientific research and development. However, many kinds of chemicals are stored in university laboratories, and some of them have the characteristics of being flammable and explosive, which increases the risk of accidents in university laboratories and easily threatens the safety of students and teaching staff, therefore, colleges and universities should pay attention to the laboratory safety management and control work, timely detection of security risks, improve laboratory safety. This paper describes the current situation of laboratory management in colleges and universities, and puts forward some safety control measures to provide reference for laboratory management.

For the experimental research of Xinjiang oilfield, all kinds of research work can not be separated from experiments. As an important place of scientific and technological research and development, the quality and level of scientific and technological research and development are directly affected by the management of the laboratory, therefore, it is of great significance to do a good job in the management of the laboratory. According to the actual situation of laboratory work, this paper summarizes the experience of laboratory management, and puts forward and implements the innovation mechanism of safety autonomous management in the course of experimental research from the aspects of creating safety concept culture and establishing standardized management mode, etc., the purpose of this paper is to promote the high-quality and high-efficiency of scientific research and production by improving the management of laboratories in oil-field scientific research units, it provides guarantee for Xinjiang oilfield to create greater economic benefits.

Aiming at the common problems existing in the scientific research laboratories of universities, such as the low level of information management, the unclear responsibility of laboratory management, the lack of equipment maintenance in the later stage and the low utilization ratio of instruments and equipment, this study proposes a"Flexible" laboratory management mechanism to solve the bottleneck problem of laboratory management. “Flexible management" is to optimize all kinds of existing soft and hard resources into a "Flexible" whole by establishing an information-based management platform, the invention solves the problems of low utilization rate of laboratory and instrument equipment, repeated purchase of the same kind of equipment, and difficulty in late-stage maintenance of equipment. Therefore, it is an inexorable trend of engineering laboratory construction to construct an efficient and extensible flexible mechanism.

Objective Establishment of a capillary column headspacesampling program for Gas chromatography determination of ethanol residuein Isosorbide Mononitrate sustained-release tablets. Methods A capillarycolumn $\left({{30}\mathrm{\;m}\times {0.320}\mathrm{\;{mm}},{0.25\mu}\mathrm{m}}\right)$ with $6\%$ cyanopropylphenyl-94%dimethylpolysiloxane (or similar polarity) as stationary solution wasused. The starting temperature was ${50}^{\circ }\mathrm{C}$ and maintainedfor $6\mathrm{\;{min}}$ , thetemperature of the detector was ${250}^{\circ }\mathrm{C}$ , thetemperature of the inlet was ${200}^{\circ }\mathrm{C}$ , theequilibrium temperature of the headspace bottle was ${80}^{\circ }\mathrm{C}$ , the equilibriumtime was ${30}\mathrm{\;{min}}$ , theflow rate of nitrogen was $1\mathrm{\;{mL}}/\mathrm{{min}}$ , and thetemperature of the headspace bottle was ${200}^{\circ }\mathrm{C}$ . The shuntratio was ${50}: 1$ . Results Underthe above chromatographic conditions, the retention time of ethanol was $3\mathrm{\;{min}}$ and theconcentration of ethanol was in the range of ${0.43}\sim {10.8\mu}\mathrm{g}/\mathrm{{mL}}$ . The recoveries were ${87.04}\%\sim {94.45}\%,\mathrm{{RSD}}={0.17}\%\left({n = 6}\right)$ .

Objective To improve the precision and accuracy of atomicfluorescence spectrometry for the determination of total seleniumcontent. Methods This article analyzes the factors affecting thedetermination of total selenium in geochemical samples by hydridegeneration atomic fluorescence spectrometry, and explores threeinfluencing factors: sample digestion, instrument cleanliness, andcoexisting ion interference. Optimized the sample digestion process,summarized the issues that should be noted in the instrument during thesample determination process, as well as the common methods foridentifying and eliminating coexisting ion interference. Results Thefeasibility of the method has been verified through 13 national firstlevel standard reference materials, the detection limit of the method is ${0.006}\mathrm{{mg}}/\mathrm{{kg}}$ ,which is lower than the detection limit of DZ/T 0279.14-2016 (0.01mg/kg). The relative standard deviation of the test standard substancewere ${1.9}\%\sim {7.9}\%$ , and $\left|{\Delta\mathrm{{lg}}C}\right|$ were all less than 0.1 . The precisionand accuracy meet the requirements of DZ/T0011-2015 Geochemical CensusSpecification (1:50000). Conclusion Effectively solved the problem ofunstable quality in the determination of total selenium by atomicfluorescence spectroscopy, and improved precision and accuracy.

Objective To determine the inhibitory effect of skin resident bacteria under the action of different preservatives. Methods Combined with the collected real-time data, the minimum inhibitory concentration value (MIC) was calculated first, the initial constraint conditions were set, and then the bacteria were cultured. The change state of the number of colonies was compared in multiple cycles, and the average value of colony change was calculated to determine and analyze the treatment effect of the bacteria at this time. The test solution was diluted batch by batch, and the inhibition and killing pairs of bacteria were calculated according to the comparison of four test targets: aqueous solution, paste cosmetics, powder cosmetics and liquid cosmetics. Results Under different sample concentration, the resident bacteria of skin were killed and inhibited. After multi-level calculation, the final killing pair value was higher, which could reach more than 7.5. Conclusion The inhibitory effect of increasing the concentration of preservatives on resident bacteria in the skin is basically in a positive change relationship. The higher the concentration of preservatives, the better the inhibitory effect will be formed; conversely, the lower the concentration of preservatives, the relatively poor inhibitory effect will be formed.

Objective To establish a method for the detection of cyclicaldehyde compounds in drinking water sources, in order to practice highquality development and improve the technical support of public servicequality. Methods Quantitative detection method of cyclic aldehydecompounds in drinking water by using SPME-GC-MS/MS were established.Results The results show that the optimal conditions for SPME aimed atcyclic aldehyde compounds in drinking water are an incubationtemperature of ${50}^{\circ }\mathrm{C}$ , a rotationalspeed of ${500}\mathrm{r}/\mathrm{{min}}$ , anincubation duration of ${15}\mathrm{\;{min}}$ , followed by asample extraction time of ${20}\mathrm{\;{min}}$ . The detectionlimits of this quantitative detection method were 2.87~4.67 ng/ L, therelative standard deviation were 6%~16%, the recoveries were 70.7%~115%.A specific water sample was collected to ascertain that the keyodor-causing compound was2-EDD, exhibiting concentrations ${32}\mathrm{{ng}}/\mathrm{L}$ . Conclusion This method can accurately and swiftly identify key odor-causingcompounds in drinking water.

Objective To explore the clinical significance of thecombined detection of fasting blood glucose and glycosylated hemoglobinin the diagnosis and treatment of diabetes. Methods From January 2023 toJanuary 2024,50 healthy people in our hospital were selected as thecontrol group, and 50 diabetes patients in our hospital at the same timewere selected as the observation group. Compare the fasting bloodglucose (FPG), glycated hemoglobin (HbA1c) levels, HbA1c, FPG, and oralglucose tolerance test (OGTT) blood glucose test results, combined andsingle test results after 2 hours of OGTT glucose administration, aswell as the correlation between HbA1c and FPG in the observation group.Results The blood glucose levels, HbA1c, and FPG of the observationgroup after 2 hours of OGTT administration were higher than those of thecontrol group $\left({P<{0.05}}\right)$ . The observation group showed a positivecorrelation between HbA1c and FPG $(r={0.608}$ , $P <{0.05}$ ).The specificity, sensitivity, and accuracy of HbA1c and FPG combineddetection are superior to single detection $\left({P <{0.05}}\right)$ . Conclusion The combined detection of HbA1c and FPG has high diagnostic accuracy fordiabetes, reduces the rate of misdiagnosis and missed diagnosis, canspeed up the diagnosis of diabetes, is conducive to early treatment, andis worth promoting.