In recent years, laboratory accidents in colleges and universities have occurred from time to time, and controlling laboratory safety has been the focus of university managers in recent years. In the practice of whole-process laboratory management, further exploration is needed. Combined with the current situation of the laboratory where the management of temporary hazards is difficult, the equipment is incompatible with the laboratory environment, and the improvement of students' safety literacy is limited, it is proposed to integrate the concept of dynamic management into the whole process management process, and realize the whole process dynamic safety management of the four elements of personnel, reagents, equipment and environment with the help of the school laboratory safety intelligent monitoring and control system, which can effectively improve the whole process management process of the laboratory.

With the development of modern medicine, fluorescence immunochromatography plays an important role in the detection of pathogenic microorganisms because of its rapid, simple and high sensitivity. In this paper, the principle and application process of the technique are systematically described, including sample pretreatment, preparation of fluorescently labeled antibodies, assembly of immunochromatographic apparatus, detection reaction and result interpretation. The application examples of the technology in the detection of bacteria, viruses and fungi were introduced, and the advantages and challenges of the technology were analyzed. The results show that fluorescence immunochromatography provides an effective tool for rapid identification and monitoring of pathogenic microorganisms, and has a wide application prospect in clinical diagnosis and public health.

This paper aims to explore the safety management construction of engineering laboratories in higher education, focusing on two aspects: safety management in engineering laboratories and the efficiency of laboratory equipment use. Specifically, safety management construction includes equipment usage safety, safety protocols for high-altitude operations in engineering testing venues, and management of external personnel. A scientifically sound management system can effectively reduce equipment usage risks and ensure testing safety. For high-altitude operations, which are common high-risk activities, strict safety regulations and emergency plans must be established to ensure the safety of operators. Additionally, managing the access of external personnel should not be neglected; it is essential to clarify their access rights and safety responsibilities to enhance the overall safety measures of the laboratory. By strengthening these three aspects of management and improving equipment usage efficiency while reducing idle and loss rates, we can not only effectively enhance the safety of the laboratory but also promote the high-quality development of engineering education.

Laboratory safety accidents have occurred from time to time, and their harm and impact are far-reaching. In view of the characteristics of agricultural laboratory, such as high density and strong mobility of personnel, diversified and complex instruments and equipment, large types and quantities of chemicals, many kinds of wastes and complex components, etc., combined with the problems in safety management, countermeasures are proposed in terms of funding investment, management system, daily management level, safety inspection, safety education, providing a solid foundation for building a safer and more harmonious laboratory environment and reliable guarantee for the school to achieve the construction of a "Double First Class" university.

Objective To solve the zero drift problem of Coriolis mass flowmeter. Methods The zero calibration method based on Prolink industrial control software was used to measure and zero the CMF mass flowmeter, and data on indication error and repeatability were obtained. Results Before zeroing, the reading error of the Coriolis mass flowmeter was measured to be -0.85%, and it was calculated that there was zero drift. After zero calibration, the indication error of the flowmeter is -0.12%, and the measurement performance meets the requirements of the accuracy level. Conclusion After using Prolink industrial control software to adjust the zero value of the flowmeter, the influence of zero drift on the phase difference offset of the flowmeter can be eliminated, thereby improving the measurement accuracy of the flowmeter.

Objective To establish a titration method for evaluating the uncertainty in the determination of thiomersal content in adsorbed diphtheria, tetanus, and acellular pertussis combined vaccine, and to identify the sources of significant uncertainty, improve laboratory detection ability. Methods The titration method was established according to the first method of the General Rules 3115 in the 2020 edition of the Pharmacopoeia of the People’s Republic of China, a mathematical model was established, and the sources of uncertainty in the detection process were analyzed to synthesize the standard uncertainty and extended uncertainty. Results In the determination of thiomersal content, all influencing factors have a certain effect. After type A evaluation and type B evaluation, the extended uncertainty${U}_{\mathrm{{rel}}}= {4.72}\%\left({K = 2}\right)$was obtained. Conclusion After evaluating the uncertainty introduced by each factor, it was found that the factors introducing significant uncertainty are mainly the titration process of the test sample. It is suggested that the titration process in low-temperature and other conditions be considered in subsequent method improvements.

Objective To observe the test results and substantial impact of real-time fluorescence quantitative PCR detection technology in detecting hepatitis B virus DNA. Methods 1500 patients with hepatitis B from January 2023 to December 2023 were selected for the study data, and all of them were detected by serological markers and real-time fluorescent quantitative PCR. The control standard was the clinical diagnosis results, and the comparison index was the DNA quantitative detection results. Results Among the 1500 confirmed hepatitis B patients, real-time fluorescence quantitative PCR technology detected hepatitis B virus DNA quantification results, which showed that the viral load of 1380 patients (92.00%) could be clearly quantified, while the serological marker method could only clearly quantify the viral load of 1260 patients (84.00%). In addition to technology, factors that may affect the final test results include laboratory operations, sample and nucleic acid extraction, and storage at multiple stages. Conclusion Real time fluorescence quantitative PCR technology has higher sensitivity and accuracy compared to traditional serum blood marker detection methods, and is more suitable for modern laboratory medicine.

This study aims to explore effective control methods for testing standards in medical device testing laboratories, in order to improve the reliability and consistency of testing results. The research adopts a combination of literature analysis and measure analysis to systematically sort out the key links of detection standard control. Research has shown that taking comprehensive measures is crucial for controlling testing standards, significantly improving the quality and credibility of medical device testing, and providing strong support for ensuring patient safety and promoting industry development.

For China's booming robot market, robot testing is a key link to ensure the performance and quality of robots, and quality control methods are also crucial for robot testing laboratories. In view of the problems faced by quality control methods in the application of robot testing laboratories, this paper analyzed and discussed the strategies of robot testing laboratories in the application of quality control methods to control testing quality, and effectively improved the accuracy and reliability of testing data and ensured the quality of robot products through the scientific and planned implementation of quality control.

Objective The structure and composition of Shoushan tianhuang were determined, and in order to understand the reason why field-yellow stone is different from other varieties of koreite. Methods It’s structure was observed by microscope and scanning electron microscope, and it’s chemical composition was analyzed by near infrared spectrometer, X-ray powder diffractometer and ICP-MS. Results By scanning electron microscopy, it was found that the crystal structure of fShoushan tianhuang is aphanocrystalline, the crystal is lamellar, the particle size is uneven, the overall orientation is poor, there is idiomorphic or hemidiomorphic pyrite and the particle boundary is clear. Comparing and analyzing the data, it is found that$\mathrm{{Cr}}$element is stable and there are three kinds of mineral composition in Shoushan tianhuang: illite is the main mineral. The main mineral is the dickite and the secondary mineral is the illite. The main minerals are dickite and kaolinite. Conclusion The analysis of structure and chemical composition of Shoushan tianhuang is of great value for identifying varieties of koreite and distinguishing different mining areas, and also provides important data support for understanding the production state and particularity of Shoushan tianhuang.