The year 2026 marks the centenary of the birth of Mr. Yu Min, a distinguished scientist who made outstanding contributions to China's "two bombs and one satellite" program and a recipient of the Medal of the Republic. As one of the leading figures in China's nuclear weapons theoretical research and advanced defense technology development, and as a key contributor to the breakthrough in hydrogen bomb principles, Yu Min, together with Peng Huanwu, Zhu Guangya, Deng Jiaxian, and other scientists, pioneered an independent path for nuclear weapons development under extremely difficult conditions. Drawing on firsthand accounts from those who worked with him, and on the basis of a systematic review of Yu Min's scientific career, this paper further distills and elucidates the generative logic, specific manifestations, and practical value of the six dimensions of his scientific spirit—patriotism, innovation, pragmatism, dedication, collaboration, and education. Yu Min's scientific spirit embodies both philosophical depth and personal inspiration. Against the strategic backdrop of the Fourth Plenary Session of the 20th Central Committee of the Communist Party of China, which set the goal of "achieving high−level scientific and technological self−reliance and building a world leader in science and technology," studying and promoting this spirit holds urgent and profound significance for our times. It inspires scientific and technological workers to keep the country's overall interests at heart, boldly venture into uncharted innovation frontiers, uphold truth−seeking and pragmatism, devote themselves selflessly, enhance collaborative efficiency, and cultivate a contingent of strategic scientists.