The rapid development of artificial intelligence is driving a new wave of scientific and technological revolution. In materials science, it is promoting the transformation of data−driven materials R&D systems, represented by Materials Genome Engineering, from an experience−driven model toward an integrated mode combining data−driven approaches with intelligent design. Focusing on the paradigm shift in materials R&D driven by the integration of high−throughput computing and machine learning, this review systematically summarizes the evolution of materials R&D paradigms, the key technological systems of high−throughput computing and machine learning, strategic layouts and progress in platform construction in China and abroad, and analyzes their impacts on the ecosystem of the advanced materials industry, scientific research organization models, and R&D pathways for key materials. High−throughput computing supports materials data generation and large−scale screening, while machine learning facilitates closed−loop iteration in intelligent materials design through rapid pre−screening and knowledge discovery, shifting competition in materials innovation from individual technological capabilities to the integrated capabilities of data resources, computational tools, R&D platforms, and organizational systems. China has initially established a relevant foundation and competitiveness in this field, and future efforts may further focus on improving the autonomy of core software, accumulating high−quality data, refining standard systems, and strengthening the integration of the R&D chain with the industrial chain. The deep integration of high−throughput computing and machine learning is driving the evolution of materials R&D from the fourth paradigm to the fifth paradigm and is continuously reshaping the technological system, industrial ecosystem, and research organization logic of advanced materials innovation.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |